抗球蛋白试验观察。II. 红细胞上的C4成分。

Observations on the antiglobulin tests. II. C4 components on erythrocytes.

作者信息

Stratton F, Rawlinson V I

出版信息

Vox Sang. 1976;31(1 SUPPL):44-54. doi: 10.1111/j.1423-0410.1976.tb02222.x.

DOI:10.1111/j.1423-0410.1976.tb02222.x

Abstract

This paper describes anti-C4b(ii) antisera shich agglutinate cells from cases of autoimmune haemolytic anaemia, cold-acquired haemolytic anaemia, and certain test cells, using the antiglobulin test. It is suggested that these particular antisera possess activity against C4d absorbed on to erythrocytes. Methods of preparing test cells coated with C3d and C4d are given, together with methods for producing antisera in rabbits active against these components. The significance of these findings is discussed.

摘要

本文描述了抗C4b（ii）抗血清，该抗血清可利用抗球蛋白试验凝集自身免疫性溶血性贫血、冷获得性溶血性贫血病例的细胞以及某些试验细胞。有人提出，这些特殊抗血清对吸附在红细胞上的C4d具有活性。文中给出了制备包被有C3d和C4d的试验细胞的方法，以及在兔体内制备对这些成分有活性的抗血清的方法。并讨论了这些发现的意义。

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