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75岁及以上有症状和无症状患者的颈动脉内膜切除术:围手术期死亡率和中风风险率

Carotid endarterectomy in symptomatic and asymptomatic patients aged 75 years or more: perioperative mortality and stroke risk rates.

作者信息

Ballotta E, Da Giau G, Saladini M, Abbruzzese E

机构信息

Vascular Surgery Section of the 1st Institute of General Surgery, University of Padua, School of Medicine, Padua, Padova, Italy.

出版信息

Ann Vasc Surg. 1999 Mar;13(2):158-63. doi: 10.1007/s100169900234.

Abstract

The aim of this retrospective study was to determine whether age per se constitutes a contraindication to surgery in the elderly patient undergoing carotid endarterectomy (CEA) with regard to operative mortality and stroke risk morbidity. During an 8-year period, 96 patients aged 75 years or more underwent 103 CEAs. The age range was 75 to 89 years, with a median age of 79 and a mean age of 79.4 years. Fifty-nine CEAs with patch closure and 44 carotid eversion endarterectomies and reimplantation were performed for symptomatic (70.9%) and asymptomatic (29.1%) carotid lesions under general anesthesia and with continuous perioperative electroencephalographic (EEG) monitoring. In light of the efficacy and success achieved in this experience, advanced age does not seem in itself to contraindicate the performance of CEA; the surgical risk for elderly patients appears sufficiently low to justify the operation. A more aggressive approach may be warranted in elderly patients because of the morbidity and cost of the disease that it effectively prevents.

摘要

这项回顾性研究的目的是,就手术死亡率和中风风险发病率而言,确定年龄本身是否构成老年患者接受颈动脉内膜切除术(CEA)的手术禁忌证。在8年期间,96例75岁及以上的患者接受了103次颈动脉内膜切除术。年龄范围为75至89岁,中位年龄为79岁,平均年龄为79.4岁。针对有症状(70.9%)和无症状(29.1%)的颈动脉病变,在全身麻醉和围手术期持续脑电图(EEG)监测下,进行了59次带补片修补的颈动脉内膜切除术以及44次颈动脉外翻内膜切除术和再植入术。鉴于本次经验所取得的疗效和成功,高龄本身似乎并不构成颈动脉内膜切除术的禁忌证;老年患者的手术风险似乎足够低,足以证明该手术的合理性。由于该手术能有效预防的疾病的发病率和成本,对老年患者可能需要采取更积极的治疗方法。

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