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Human outer dense fiber gene, ODF2, localizes to chromosome 9q34.

作者信息

Shao X, Murthy S, Demetrick D J, van der Hoorn F A

机构信息

Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada.

出版信息

Cytogenet Cell Genet. 1998;83(3-4):221-3. doi: 10.1159/000015183.

DOI:10.1159/000015183
PMID:10072582
Abstract

We have isolated the human homolog of the rat Odf2 gene. In rat, Odf2, the 84-kDa major outer dense fiber protein, interacts strongly and specifically with Odf1, the 27-kDa major outer dense fiber protein. The interaction is mediated by leucine zippers during ODF assembly along the sperm axoneme. We compared homology and genomic structure to rat and mouse Odf2 genes. Using fluorescence in situ hybridization, we mapped the human Odf2 gene (ODF2) to chromosome 9q34.

摘要

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Human outer dense fiber gene, ODF2, localizes to chromosome 9q34.
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