美国孕妇的身体活动和久坐行为与生物标志物的关联。
Association of physical activity and sedentary behavior with biological markers among U.S. pregnant women.
机构信息
1 Department of Exercise Science, Donna and Allan Lansing School of Nursing and Health Sciences, Bellarmine University , Louisville, Kentucky.
出版信息
J Womens Health (Larchmt). 2013 Nov;22(11):953-8. doi: 10.1089/jwh.2013.4394. Epub 2013 Aug 22.
BACKGROUND
To examine the association between objectively measured light-intensity and moderate-to-vigorous-intensity physical activity (MVPA), sedentary behaviors, and biological markers in a national sample of U.S. pregnant women, as few studies have examined these relationships among this population.
METHODS
The sample of noninstitutionalized U.S. civilians was selected by a complex, multistage probability design. Data from the 2003-2006 National Health and Examination Survey were used. Two hundred six pregnant women were included in the data analysis. Physical activity and sedentary data were objectively measured via accelerometry (ActiGraph 7164). Biomarker data was obtained in the mobile examination center from urine, blood samples, blood pressure, and anthropometric measurements. Urine and blood samples were obtained to determine pregnancy status, C-reactive protein (CRP), high-density lipoprotein (HDL) cholesterol, total cholesterol, and cotinine as well as fasting glucose, fasting triglycerides, and fasting low-density lipoprotein (LDL) cholesterol data. Multivariable regression was employed to examine the association between physical activity, sedentary behavior, and biomarker levels.
RESULTS
There was a positive association between sedentary behavior and CRP levels (beta coefficient [b]=0.001, p=0.02) and LDL cholesterol (b=0.12, p=0.02). There was an inverse association between light-intensity physical activity and CRP (b=-0.003; p=0.008) and diastolic blood pressure (b=-0.03; p=0.02), with those engaging in higher levels of MVPA having higher HDL cholesterol (b=6.7; p=0.01).
CONCLUSION
Physical activity and sedentary behavior were favorably associated with various biomarkers among pregnant women, suggesting that healthcare providers should encourage pregnant women to participate in safe forms of physical activity behaviors while also reducing their amount of time spent in sedentary behaviors.
背景
为了在美国孕妇的全国样本中检查客观测量的光强度与中等到剧烈强度的身体活动（MVPA）、久坐行为和生物标志物之间的关联，因为很少有研究在这一人群中检查这些关系。
方法
非机构化的美国平民样本是通过复杂的、多阶段概率设计选择的。使用了 2003-2006 年全国健康和体检调查的数据。数据分析中包括 206 名孕妇。通过加速度计（ActiGraph 7164）客观测量身体活动和久坐数据。生物标志物数据是在移动体检中心从尿液、血液样本、血压和人体测量中获得的。尿液和血液样本用于确定妊娠状态、C 反应蛋白（CRP）、高密度脂蛋白（HDL）胆固醇、总胆固醇和可替宁以及空腹血糖、空腹甘油三酯和空腹低密度脂蛋白（LDL）胆固醇数据。多变量回归用于检查身体活动、久坐行为和生物标志物水平之间的关联。
结果
久坐行为与 CRP 水平（β系数[b]=0.001，p=0.02）和 LDL 胆固醇（b=0.12，p=0.02）呈正相关。轻度体力活动与 CRP 呈负相关（b=-0.003；p=0.008）和舒张压（b=-0.03；p=0.02），而进行更高水平的 MVPA 的人具有更高的 HDL 胆固醇（b=6.7；p=0.01）。
结论
身体活动和久坐行为与孕妇的各种生物标志物呈正相关，这表明医疗保健提供者应鼓励孕妇参与安全的身体活动行为，同时减少他们久坐的时间。
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