Pereira M A, Folsom A R, McGovern P G, Carpenter M, Arnett D K, Liao D, Szklo M, Hutchinson R G
Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota 55455-1015, USA.
Prev Med. 1999 Mar;28(3):304-12. doi: 10.1006/pmed.1998.0431.
The epidemiologic observation that physical activity reduces the risk for hypertension has only been made for white men who self-reported hypertension. This study examined physical activity and clinically determined incident hypertension in black and white men and women of the Atherosclerosis Risk in Communities (ARIC) Study.
ARIC is a population-based prospective study with four U.S. clinic centers. The present analyses included 7,459 black and white adults 45-65 years of age. Hypertension (systolic/diastolic blood pressure >/= 140/90 mm Hg) was defined by blood pressure measured by a random-zero device or medication use. Physical activity was assessed with the Baecke questionnaire.
After adjustment for age, baseline blood pressure, ARIC center, education, body mass index, waist-hip ratio, parental history of hypertension, cigarette smoking, alcohol consumption, and diet, white men in the highest quartile of leisure activity (primarily cycling and walking) had a 34% lower odds of developing hypertension over 6 years compared to the least active (OR = 0.66, 95% CI = 0.47-0.94; P for quartile trend = 0.01). Baseline activity was not associated with incident hypertension in white women or blacks.
Leisure-time physical activity reduces the odds of hypertension in middle-aged white men. Additional studies in women and blacks are needed.
流行病学观察发现,体育活动可降低高血压风险,这一结论仅基于自我报告患有高血压的白人男性得出。本研究在社区动脉粥样硬化风险(ARIC)研究中的黑人和白人男性及女性群体中,调查了体育活动与临床确诊的新发高血压之间的关系。
ARIC是一项基于人群的前瞻性研究,在美国设有四个临床中心。本次分析纳入了7459名年龄在45至65岁之间的黑人和白人成年人。高血压(收缩压/舒张压≥140/90毫米汞柱)通过随机零点血压计测量的血压或药物使用情况来定义。体育活动通过贝克问卷进行评估。
在对年龄、基线血压、ARIC中心、教育程度、体重指数、腰臀比、高血压家族史、吸烟、饮酒和饮食进行调整后,与活动最少的白人男性相比,休闲活动处于最高四分位数(主要为骑自行车和步行)的白人男性在6年内患高血压的几率低34%(比值比=0.66,95%置信区间=0.47-0.94;四分位数趋势P值=0.01)。基线活动与白人女性或黑人的新发高血压无关。
休闲体育活动可降低中年白人男性患高血压的几率。还需要对女性和黑人进行更多研究。