Booker Robert, Beech Bettina M, Bruce Marino A, Thorpe Roland J, Norris Keith C, Heitman Elizabeth, Newton Robert L, Holmes Megan E
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA (RB); University of Houston Population Health, University of Houston, Houston, TX, USA (BMB); Department of Health Systems and Population Health Sciences, University of Houston Tilman J. Fertitta Family College of Medicine, Houston, TX, USA (BMB, MAB); Program for Research on Men's Health, Hopkins Center for Health Disparities Solutions, John Hopkins Bloomberg School of Public Health, Baltimore, MD, USA (BMB, MAB, RJT, KCN); Program for Research on Faith, Justice, and Health, Department of Behavioral and Social Sciences, University of Houston Tilman J. Fertitta Family College of Medicine, Houston, TX, USA (MAB, RJT, KCN, EH); Division of General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA (KCN); Program in Ethics in Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA (EH); Pennington Biomedical Research Center, Baton Rouge, LA, USA (RLN); Department of Kinesiology, Mississippi State University, Mississippi State, MS, USA (MEH).
Am J Lifestyle Med. 2022 Aug 15;19(4):561-571. doi: 10.1177/15598276221118044. eCollection 2025 May-Jun.
Cross-sectional investigation of the association of sedentary behavior and physical activity with metabolic syndrome (MetS) among the African American participants in the Jackson Heart Study (JHS). Prevalence, number of individual components, and MetS severity -score (MetS-Z) were examined. MetS was classified using ATP-III thresholds. MetS-Z was calculated using sex-, race-, and ethnicity-specific formulas. Sedentary behavior and physical activity were calculated from the JHS Physical Activity Cohort survey (JPAC). Associations between sedentary behavior and physical activity with MetS were assessed by logistic, negative binomial, and ordinary least squares regressions. The mean participant age ( = 3370) was 61.7 ± 11.9 years and most were female (63.9%). Among all participants, 60.5% were classified with MetS. Overall MetS-Z was moderately high (.31 ± 1.07). Most waking hours were sedentary, with just under 40 daily minutes of self-reported physical activity. Physical activity was associated with lower prevalence of MetS, the number of individual components, and MetS-Z score ( < .05). Sedentary behavior was not associated with MetS in any fully adjusted models ( > .05). Physical activity was associated with lower cardiometabolic risk, irrespective of sedentary behavior. Further studies are needed to better understand why no relation was found between sedentary behavior and cardiometabolic risk in this cohort of African American adults.
杰克逊心脏研究（JHS）中非洲裔美国参与者久坐行为和身体活动与代谢综合征（MetS）关联的横断面调查。研究了患病率、个体组分数量以及代谢综合征严重程度评分（MetS-Z）。采用ATP-III阈值对代谢综合征进行分类。使用性别、种族和民族特异性公式计算MetS-Z。久坐行为和身体活动通过JHS身体活动队列调查（JPAC）进行计算。通过逻辑回归、负二项回归和普通最小二乘法回归评估久坐行为和身体活动与代谢综合征之间的关联。平均参与者年龄（n = 3370）为61.7±11.9岁，大多数为女性（63.9%）。在所有参与者中，60.5%被归类为患有代谢综合征。总体MetS-Z处于中等偏高水平（0.31±1.07）。大多数清醒时间都处于久坐状态，自我报告的每日身体活动时间不足40分钟。身体活动与较低的代谢综合征患病率、个体组分数量以及MetS-Z评分相关（P < 0.05）。在任何完全调整模型中，久坐行为与代谢综合征均无关联（P > 0.05）。无论久坐行为如何，身体活动都与较低的心脏代谢风险相关。需要进一步研究以更好地理解为何在这一非洲裔美国成年人队列中未发现久坐行为与心脏代谢风险之间的关系。
