Xu L, Gao M, Yao T
Pulmonary Division, Anzhen Hospital, Beijing.
Zhonghua Jie He He Hu Xi Za Zhi. 1997 Apr;20(2):72-5.
Study of mechanical ventilation (MV) therapy of ARDS (acute respiratory distress syndrome).
Ten cases of ARDS were observed. Depending on patients' kidney compensation for respiratory acidosis, low tidal volume (VT, mean = 6.5 ml/kg) was used and certain respiratory acidosis was permitted in order to decrease airway plateau pressure and lung barotrauma. On the premise of keeping patients' PaO2 about 7.3 kPa (1 kPa = 7.5 mmHg), lowest possible FiO2 (mean = 0.51) and PEEP (mean = 0.92 kPa, 1 kPa = 10.2 cmH2O) were used.
Seven of the ten survived. Three of them had respiratory acidosis and two had lung barotrauma during MV.
Using lower VT and permitting certain respiratory acidosis are worthy to be considered in MV therapy of ARDS.
