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[肌张力障碍的治疗]

[Treatment of dystonias].

作者信息

Marion M H

机构信息

Clinique Turin, Paris.

出版信息

Presse Med. 1999 Feb 13;28(6):312-5.

Abstract

UNLABELLED

SYMPTOMATIC TREATMENT: Treatment of idiopathic dystonia depends on the age of onset and the extent of the disease. Symptomatic treatment has made many advances over the last 20 years.

CHILDHOOD ONSET GENERALIZED DYSTONIA

In childhood onset cases, it is important first to exclude dopa-responsive dystonia. Most of these patients will respond subsequently to high dose anticholinergics.

ADULT ONSET FOCAL DYSTONIA

Treatment of this form has been transformed by botulinum toxin therapy.

TREATMENT

The treatment of each focal dystonia (blepharospasm, spasmodic torticollis, oromandibular dystonia, laryngeal dystonia, writer's cramp, foot dystonia and axial dystonia) are reviewed. Treatments must be titrated carefully. Botulinum toxin injections require precision and must be repeated regularly. A rehabilitation program must be adapted to each individual. Surgery, in very severe cases, requires an extensive well-planned discussion of indications.

摘要

未标注

对症治疗:特发性肌张力障碍的治疗取决于发病年龄和疾病程度。在过去20年中,对症治疗取得了许多进展。

儿童期起病的全身性肌张力障碍

在儿童期起病的病例中,首先排除多巴反应性肌张力障碍很重要。这些患者中的大多数随后会对高剂量抗胆碱能药物产生反应。

成人期起病的局灶性肌张力障碍

肉毒毒素疗法改变了这种类型的治疗。

治疗

对每种局灶性肌张力障碍(眼睑痉挛、痉挛性斜颈、口下颌肌张力障碍、喉肌张力障碍、书写痉挛、足部肌张力障碍和轴性肌张力障碍)的治疗进行了综述。治疗必须仔细滴定。肉毒毒素注射需要精确操作,且必须定期重复。康复计划必须因人而异。在非常严重的情况下,手术需要就适应症进行广泛且精心规划的讨论。

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