Taylor S K, Williams E S, Pier A C, Mills K W, Bock M D
Department of Veterinary Sciences, University of Wyoming, Laramie 82070, USA.
J Wildl Dis. 1999 Jan;35(1):70-4. doi: 10.7589/0090-3558-35.1.70.
During late May 1995, 50 adult captive endangered Wyoming toads (Bufo baxteri) were brought out of hibernation. Approximately 3 to 10 days after hibernation emergence, all toads were hormonally induced to breed, and paired. Each pair was placed in their own breeding tank. Four toads developed clinical signs of disease which included lethargy and multiple (4 to 12) small (2 mm) raised hyperemic nodules with white fuzzy caps on the ventral skin. The condition progressively worsened until death occurred, within 3 to 6 days. Mycotic dermatitis caused by Mucor sp. was diagnosed in the four toads through histology and isolation of the organism. This is the first case report of a Mucor sp. causing a fatal dermatitis in an amphibian without significant inflammatory response and without systemic involvement.
1995年5月下旬，50只圈养的成年濒危怀俄明蟾蜍（巴氏蟾蜍）结束冬眠。冬眠结束后约3至10天，所有蟾蜍均通过激素诱导进行繁殖并配对。每对蟾蜍被放置在各自的繁殖缸中。4只蟾蜍出现了疾病的临床症状，包括嗜睡以及腹部皮肤出现多个（4至12个）小（2毫米）的凸起充血结节，结节上有白色绒毛状帽。病情逐渐恶化，直至在3至6天内死亡。通过组织学检查和病原体分离，在这4只蟾蜍中诊断出由毛霉属引起的霉菌性皮炎。这是首例关于毛霉属在两栖动物中引起致命性皮炎且无明显炎症反应和无全身受累的病例报告。
