乳汁分泌变化对食物限制或窝仔数增加所致哺乳期不育延长的影响。

The contribution of changes in milk delivery to the prolongation of lactational infertility induced by food restriction or increased litter size.

作者信息

Woodside B, Popeski N

机构信息

Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, Québec, Canada.

出版信息

Physiol Behav. 1999;65(4-5):711-5. doi: 10.1016/s0031-9384(98)00210-8.

DOI:10.1016/s0031-9384(98)00210-8

PMID:10073472

Abstract

In rats, the length of lactational anovulation is prolonged when litter size is increased or when the dam is food restricted. In both of these situations the energetic demand on the dam is increased, milk delivery to each pup is reduced, and consequently, patterns of pup suckling may be changed. We investigated the contribution of these factors to the maintenance of lactational anovulation by examining the effect of eliminating milk delivery on the length of lactational diestrus in food restricted and ad lib-fed females nursing litters of 8 pups and in females nursing large (14 pups) and small (6 pups) litters. The results of these studies show that preventing milk delivery neither extends the period of lactational infertility in ad lib-fed females nursing eight pups nor eliminates the effects of increasing litter size on this period.

摘要

在大鼠中，当窝仔数增加或母鼠食物受限时，哺乳期无排卵的时长会延长。在这两种情况下，母鼠的能量需求都会增加，每只幼崽获得的乳汁供应会减少，因此，幼崽的吮乳模式可能会改变。我们通过研究在食物受限和自由采食的母鼠中，切断乳汁供应对哺育8只幼崽的母鼠、哺育14只幼崽（大窝）和6只幼崽（小窝）的母鼠哺乳期间情期时长的影响，来探究这些因素对维持哺乳期无排卵的作用。这些研究结果表明，切断乳汁供应既不会延长自由采食且哺育8只幼崽的母鼠的哺乳期不育期，也不会消除窝仔数增加对这一时期的影响。