Adish A A, Esrey S A, Gyorkos T W, Jean-Baptiste J, Rojhani A
School of Dietetics and Human Nutrition, McGill University, St Anne-de-Bellevue, Quebec, Canada.
Lancet. 1999 Feb 27;353(9154):712-6. doi: 10.1016/S0140-6736(98)04450-X.
In less-developed countries, novel strategies are needed to control iron-deficiency anaemia, the most common form of malnutrition.
We undertook a community-based randomised controlled trial to assess the effects of iron or aluminium cooking pots in young Ethiopian children. Analysis was by intention-to-treat. The primary outcomes were change in children's haemoglobin concentration, weight, or length over the study period. We also did a laboratory study of total and available iron in traditional Ethiopian foods cooked in iron, aluminium, and clay pots.
407 children, one per household, entered the study. The change in haemoglobin concentration was greater in the iron-pot group than in the aluminium-pot group (mean change to 12 months 1.7 [SD 1.5] vs 0.4 [1.0] g/dL; mean difference between groups 1.3 g/dL [95% Cl 1.1-1.6]). The mean differences between the groups in weight and length gain to 12 months (adjusted for baseline weight or length) were 0.6 cm (95% CI 0.1-1.0) and 0.1 kg (-0.1 to 0.3). The laboratory study showed that total and available iron was greatest in foods cooked in iron pots, except for available iron in legumes for which there was no difference between types of pot.
Ethiopian children fed food from iron pots had lower rates of anaemia and better growth than children whose food was cooked in aluminium pots. Provision of iron cooking pots for households in less-developed countries may be a useful method to prevent iron-deficiency anaemia.
在欠发达国家,需要新的策略来控制缺铁性贫血,这是最常见的营养不良形式。
我们开展了一项基于社区的随机对照试验,以评估铁制或铝制炊具对埃塞俄比亚幼儿的影响。分析采用意向性分析。主要结局是研究期间儿童血红蛋白浓度、体重或身长的变化。我们还对用铁制、铝制和陶制锅烹饪的埃塞俄比亚传统食物中的总铁和可利用铁进行了实验室研究。
407名儿童(每户一名)进入研究。铁制炊具组的血红蛋白浓度变化大于铝制炊具组(至12个月时的平均变化为1.7 [标准差1.5] vs 0.4 [1.0] g/dL;组间平均差异为1.3 g/dL [95%置信区间1.1 - 1.6])。至12个月时,两组在体重和身长增加方面的平均差异(根据基线体重或身长进行调整)分别为0.6 cm(95%置信区间0.1 - 1.0)和0.1 kg(-0.1至0.3)。实验室研究表明,铁制锅中烹饪的食物总铁和可利用铁含量最高,但豆类中的可利用铁在不同类型锅中没有差异。
用铁制锅烹饪食物喂养的埃塞俄比亚儿童比用铝制锅烹饪食物喂养的儿童贫血发生率更低且生长情况更好。为欠发达国家的家庭提供铁制炊具可能是预防缺铁性贫血的一种有效方法。