苏格兰药物警戒的记录链接
Record-linkage for pharmacovigilance in Scotland.
作者信息
Evans J M, MacDonald T M
机构信息
Department of Pharmacology and Clinical Pharmacology, Ninewells Hospital and Medical School, Dundee.
出版信息
Br J Clin Pharmacol. 1999 Jan;47(1):105-10. doi: 10.1046/j.1365-2125.1999.00853.x.
Abstract
Record-linkage is the linkage of patient-specific information that is stored separately. Recent advances in computerization have meant that record-linkage techniques in medical research are increasingly being used and refined. In particular, they have made a significant contribution to pharmacovigilance, which involves linking drug exposure to outcomes data. In this article, the contribution of record-linkage in Scotland to medical research is described. The two organizations that utilize record-linkage techniques are the Medicines Monitoring Unit (MEMO) of the University of Dundee and the Information and Statistics Division (ISD) of the NHS in Scotland. Pharmacovigilance is MEMO's main concern (using data from the Tayside region of Scotland), while ISD link health care datasets for Scotland for general health care research. The experience of the two groups is now being combined to carry out drug safety studies in the entire population of Scotland.
摘要
记录链接是指对单独存储的患者特定信息进行链接。计算机化方面的最新进展意味着医学研究中的记录链接技术正越来越多地被使用和完善。特别是，它们对药物警戒做出了重大贡献，药物警戒涉及将药物暴露与结局数据相联系。在本文中，描述了苏格兰的记录链接对医学研究的贡献。利用记录链接技术的两个组织分别是邓迪大学的药物监测部门（MEMO）和苏格兰国民保健服务体系的信息与统计部门（ISD）。药物警戒是MEMO的主要关注点（使用来自苏格兰泰赛德地区的数据），而ISD则为苏格兰的一般医疗保健研究链接医疗保健数据集。现在，这两个小组的经验正在结合起来，以对苏格兰全体人口开展药物安全性研究。
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