La Vecchia L, Paccanaro M, Bonanno C, Varotto L, Ometto R, Vincenzi M
Department of Cardiology, Ospedale S. Bortolo, Vicenza, Italy.
Am J Cardiol. 1999 Jan 1;83(1):120-2, A9. doi: 10.1016/s0002-9149(98)00795-4.
Eighty-five consecutive patients with idiopathic dilated cardiomyopathy were categorized according to the presence (biventricular dysfunction) or absence (left ventricular [LV] dysfunction) of reduced right ventricular ejection fraction (<35%) along with reduced LV ejection fraction (<50%). Compared with the 36 patients with LV dysfunction, the 49 patients with biventricular dysfunction had significantly worse New York Heart Association functional class (2.7+/-0.6 vs 1.9+/-0.5; p <0.001), LV ejection fraction (26+/-10% vs 34+/-8%; p <0.0001), and outcome (transplant-free survival, 55% vs 89%; p <0.001). Thus, dilated cardiomyopathy is frequently characterized by biventricular involvement, which identifies a more severe disease and a worse long-term prognosis.
85例特发性扩张型心肌病患者根据右心室射血分数降低（<35%）伴左心室射血分数降低（<50%）的情况分为两组，即存在双心室功能障碍组（双心室功能障碍）和不存在双心室功能障碍组（左心室功能障碍）。与36例左心室功能障碍患者相比，49例双心室功能障碍患者的纽约心脏协会功能分级明显更差（2.7±0.6对1.9±0.5；p<0.001），左心室射血分数更低（26±10%对34±8%；p<0.0001），预后更差（无移植生存率，55%对89%；p<0.001）。因此，扩张型心肌病常以双心室受累为特征，这表明疾病更严重，长期预后更差。
