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肾移植后与木村病相关的局灶节段性肾小球硬化复发

Recurrence of focal segmental glomerulosclerosis associated with Kimura's disease after kidney transplantation.

作者信息

Romão J E, Saldanha L B, Ianez L E, Sabbaga E

机构信息

Renal Transplantation Unit, Urology Division, Hospital das Cl¿nicas, University of S¿o Paulo Medical School, São Paulo, Brazil.

出版信息

Am J Kidney Dis. 1998 Mar;31(3):E3. doi: 10.1053/ajkd.1998.v31.pm10074577.

Abstract

A 13-year-old Brazilian boy with Kimura's disease (eosinophylic lymphoid granuloma) and nephrotic syndrome is reported. Native kidney biopsy showed focal segmental glomerulosclerosis (FSGS). Treatment with prednisolone resulted in partial remission of proteinuria, and he had a progressive loss in renal function, requiring initiation of chronic dialysis, which he underwent for 46 months. After kidney transplantation, the patient developed proteinuria. A renal biopsy showed recurrence of focal segmental glomerulosclerosis, and subsequently he developed renal insufficiency.

摘要

报告了一名患有木村病(嗜酸性淋巴肉芽肿)和肾病综合征的13岁巴西男孩。肾活检显示局灶节段性肾小球硬化(FSGS)。泼尼松龙治疗使蛋白尿部分缓解,但他的肾功能逐渐丧失,需要开始进行慢性透析,他接受了46个月的透析。肾移植后,患者出现蛋白尿。肾活检显示局灶节段性肾小球硬化复发,随后他出现了肾功能不全。

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