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猫爪草(威尔德)DC——民族药用及新的药理、毒理和植物学研究成果

Uncaria tomentosa (Willd.) DC.--ethnomedicinal use and new pharmacological, toxicological and botanical results.

作者信息

Keplinger K, Laus G, Wurm M, Dierich M P, Teppner H

机构信息

Immodal Pharmaka GmbH, Volders, Austria.

出版信息

J Ethnopharmacol. 1999 Jan;64(1):23-34. doi: 10.1016/s0378-8741(98)00096-8.

DOI:10.1016/s0378-8741(98)00096-8
PMID:10075119
Abstract

The medicinal system of the Asháninka Indians in Perú is portrayed. Three categories of medical disorders and healers are recognized. A human is viewed to consist of a physical and a spiritual being who communicate with each other by means of a regulating element. The significance of Uncaria tomentosa (Willd.) DC. (Rubiaceae), locally known as unã de gato, in traditional medicine is emphasized by its exclusive use by priests to influence this regulation. Pharmacological and toxicological results obtained with extracts or isolated compounds are summarized. Pentacyclic oxindole alkaloids stimulate endothelial cells in vitro to produce a lymphocyte-proliferation-regulating factor. Tetracyclic oxindole alkaloids act as antagonists. A significant normalization of lymphocyte percentage was observed in vivo although total leucocyte numbers did not change.

摘要

秘鲁阿沙宁卡印第安人的医药体系被描绘了出来。人们认识到三类医学病症和治疗者。人被视为由一个物质体和一个精神体组成,它们通过一个调节元素相互交流。钩藤(茜草科),当地称为uña de gato,在传统医学中的重要性体现在牧师专门使用它来影响这种调节。总结了用提取物或分离化合物获得的药理和毒理学结果。五环氧化吲哚生物碱在体外刺激内皮细胞产生一种淋巴细胞增殖调节因子。四环氧化吲哚生物碱起拮抗剂作用。尽管白细胞总数没有变化,但在体内观察到淋巴细胞百分比有显著正常化。

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J Ethnopharmacol. 1999 Jan;64(1):23-34. doi: 10.1016/s0378-8741(98)00096-8.
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