Podboronov V M, Grokhovskaia I M, Podboronov A M
Parazitologiia. 1978 Sep-Oct;12(5):400-5.
Experiments in vivo have shown that the ticks of Ornithodoros papillipes inhibit both Gram-positive and Gram-negative bacteria. On Gram-positive microorganisms most sensitive to bactericidal effect of ticks have turned to be micrococci, staphylococci, streptococci and bacteria of diphtheria, of Gram-negative ones--Bacillus coli. Of Gram-positive microorganisms less sensitive were Listeria, of Gram-negative ones--salmonellae, agents of tularemia and pseudotuberculosis. At the infection with bacteria the organism of the tick produces a bactericidal substance which causes the dying off of the microbal population. The ability of the bactericidal substance to lyse the inhibited cells of Micrococcus lysodeiktickus as well as the coincidence of data on sensibility to the tick bactericidal substance obtained experimentally in vitro and in vivo have shown that lysozyme is an active antibacterial substance in the tick's organism.
体内实验表明,乳突钝缘蜱能抑制革兰氏阳性菌和革兰氏阴性菌。在革兰氏阳性微生物中,对蜱的杀菌作用最敏感的是微球菌、葡萄球菌、链球菌和白喉杆菌,在革兰氏阴性菌中是大肠杆菌。革兰氏阳性微生物中较不敏感的是李斯特菌,革兰氏阴性菌中是沙门氏菌、土拉菌病病原体和假结核病原体。在感染细菌时,蜱的机体产生一种杀菌物质,可导致微生物群体死亡。杀菌物质裂解溶壁微球菌受抑制细胞的能力,以及体外和体内实验获得的对蜱杀菌物质敏感性数据的一致性表明,溶菌酶是蜱机体中的一种活性抗菌物质。