Kicha A A, Kalinovsky A I, Ivanchina N V, Stonik V A
Pacific Institute of Bioorganic Chemistry of the Far East Branch of the Russian Academy of Science, Vladivostok-22, Russia.
J Nat Prod. 1999 Feb;62(2):279-82. doi: 10.1021/np980381i.
Four new 24-O-biosides of 5alpha-cholestane-3beta,6alpha,8,15beta, 24-pentaol, designated as mediasterosides M1 (1), M2 (2), M3 (3), and M4 (4), and the previously known 5alpha-cholestane-3beta,6beta,8, 15alpha,16beta,26-hexaol (5) have been isolated from the deep-water starfish Mediaster murrayi. Glycosides 1-3 contain rare carbohydrate moieties with (1-->5) bonds between the monosaccharide units. Compounds 1 and 2 showed the inhibition of cell division of fertilized sea urchin eggs and exhibited moderate hemolytic activities.
从深水海星默氏中星海星（Mediaster murrayi）中分离出了四种新的5α-胆甾烷-3β,6α,8,15β,24-戊醇的24-O-二糖苷，命名为中星海星苷M1（1）、M2（2）、M3（3）和M4（4），以及之前已知的5α-胆甾烷-3β,6β,8,15α,16β,26-己醇（5）。糖苷1-3含有稀有碳水化合物部分，单糖单元之间存在（1→5）键。化合物1和2显示出对海胆受精卵细胞分裂的抑制作用，并表现出中等程度的溶血活性。
