Whitney J D, Heitkemper M M
Department of Biobehavioral Nursing and Health Systems, University of Washington, Seattle 98195, USA.
Heart Lung. 1999 Mar-Apr;28(2):123-33. doi: 10.1053/hl.1999.v28.a97155.
Tissue injury is common among patients in acute care settings. The subsequent response to injury, wound healing, follows an intricate but well-defined sequence that, under normal conditions, proceeds to satisfactory repair. However, because of the complexity of the healing response, several factors can intervene to impair normal healing. As a better understanding of how diverse factors influence healing is gained, the use of interventions that modulate these factors becomes possible and potentially beneficial. This article reviews knowledge of perfusion, nutrition, and stress as they relate to healing in patients experiencing acute wounds. Therapeutic implications based on current research are discussed.
组织损伤在急性护理环境中的患者中很常见。随后对损伤的反应，即伤口愈合，遵循一个复杂但明确的顺序，在正常情况下，会进行到令人满意的修复。然而，由于愈合反应的复杂性，有几个因素可能会干预并损害正常愈合。随着对各种因素如何影响愈合有了更好的理解，使用调节这些因素的干预措施就变得可能且具有潜在益处。本文综述了与急性伤口患者愈合相关的灌注、营养和应激方面的知识。并讨论了基于当前研究的治疗意义。
