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法国孕妇群体中的人类免疫缺陷病毒筛查:1995年全国围产期调查结果

Human immunodeficiency virus screening among pregnant women in France: results from the 1995 National Perinatal Survey.

作者信息

Vayssière C, Du Mazaubrun C, Bréart G

机构信息

Epidemiological Research Unit on Women and Children's Health, Institut National de la Sante et de la Recherche Medicale (INSERM), Unit 149, Paris, France.

出版信息

Am J Obstet Gynecol. 1999 Mar;180(3 Pt 1):564-70. doi: 10.1016/s0002-9378(99)70255-3.

Abstract

OBJECTIVE

The aim of the study was to assess how the French legislation requiring physicians to offer human immunodeficiency virus screening routinely at the beginning of prenatal care has been implemented and to explore areas in which improvement is required.

STUDY DESIGN

The survey included all births in France during a 7-day period in February 1995. A total of 12,341 women were asked whether they knew whether they had undergone a human immunodeficiency virus antibody test before or during the pregnancy. Factors that could have influenced their knowledge of whether they had been tested were also assessed.

RESULTS

Of the women questioned, 87.3% stated that they had been tested before or during pregnancy, 7.6% said that they had not been tested, and 5.1% stated that they did not know whether a test had been performed. Among those who said that they had not been tested before the pregnancy in question, 84. 9% reported that they were tested during the pregnancy. The multivariate analysis revealed that women from North Africa differed significantly from French women in both unawareness of screening status and the proportion who reported not being screened (odds ratio 2.1 with 95% confidence interval 1.6-2.9 and odds ratio 2.4 with 95% confidence interval 1.8-3.1, respectively). There was, however, no significant difference between women from sub-Saharan Africa and French women in these variables. A lower educational level was an important predictor of unawareness of screening status (odds ratio 2.6 with 95% confidence interval 2.0-3.4). Associations were observed between reporting of unscreened status and low levels of use of prenatal care services (<6 prenatal consultations odds ratio 1.3 with 95% confidence interval 1.0-1.6, <3 ultrasonographic examinations odds ratio 1.7 with 95% confidence interval 1.3-2.0, and no prenatal consultation at the maternity hospital odds ratio 1. 5 with 95% confidence interval 1.2-1.8).

CONCLUSION

The 1995 National Perinatal Survey, which appears to indicate extensive human immunodeficiency virus screening of pregnant women in France, shows that the nonmandatory nature of the French policy of systematically offering prenatal human immunodeficiency virus screening has not prevented a high proportion of women from learning their screening status. The less comprehensive screening among women in certain subgroups suggests that human immunodeficiency virus information should be better adapted for these women.

摘要

目的

本研究旨在评估法国要求医生在产前护理开始时常规提供人类免疫缺陷病毒筛查的立法是如何实施的,并探索需要改进的领域。

研究设计

该调查涵盖了1995年2月为期7天内法国所有的分娩情况。总共询问了12341名女性是否知道她们在怀孕前或怀孕期间是否接受过人类免疫缺陷病毒抗体检测。还评估了可能影响她们是否接受过检测的知晓情况的因素。

结果

在接受询问的女性中,87.3%表示她们在怀孕前或怀孕期间接受过检测,7.6%表示未接受检测,5.1%表示不知道是否进行过检测。在那些表示在所讨论的怀孕前未接受检测的女性中,84.9%报告她们在怀孕期间接受了检测。多变量分析显示,来自北非的女性在对筛查状态的不知情以及报告未接受筛查的比例方面与法国女性有显著差异(优势比分别为2.1,95%置信区间为1.6 - 2.9;优势比为2.4,95%置信区间为1.8 - 3.1)。然而,在这些变量方面,撒哈拉以南非洲的女性与法国女性之间没有显著差异。较低的教育水平是对筛查状态不知情的一个重要预测因素(优势比为2.6,95%置信区间为2.0 - 3.4)。在报告未接受筛查状态与产前护理服务利用率低之间观察到了关联(产前咨询次数<6次,优势比为1.3,95%置信区间为1.0 - 1.6;超声检查次数<3次,优势比为1.7,95%置信区间为1.3 - 2.0;在妇产医院未进行产前咨询,优势比为1.5,95%置信区间为1.2 - 1.8)。

结论

1995年全国围产期调查似乎表明法国对孕妇进行了广泛的人类免疫缺陷病毒筛查,该调查显示法国系统性地提供产前人类免疫缺陷病毒筛查政策的非强制性性质并未阻止很大一部分女性了解她们的筛查状态。某些亚组女性的筛查不够全面表明,人类免疫缺陷病毒信息应更好地针对这些女性进行调整。

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