脂蛋白(a)水平与身体活动及冠心病家族史的关系。
Relationship of lipoprotein(a) levels to physical activity and family history of coronary heart disease.
作者信息
Martín S, Elosua R, Covas M I, Pavesi M, Vila J, Marrugat J
机构信息
Unitat de Lipids i Epidemiologia Cardiovascular (ULEC), Institut Municipal d'Investigació Mèdica (IMIM), Barcelona, Spain.
出版信息
Am J Public Health. 1999 Mar;89(3):383-5. doi: 10.2105/ajph.89.3.383.
OBJECTIVES
This study evaluated the association of physical activity with serum lipoprotein(a) [La(a)] levels in individuals according to whether they had a family history of coronary heart disease (CHD).
METHODS
Lp(a) levels in 332 healthy Spanish men aged 20 to 60 years were measured. Physical activity and family history of CHD were assessed.
RESULTS
For men with a family history of CHD, the odds ratio for Lp(a) levels above the median value was 0.13 (95% confidence interval = 0.03, 0.50) in very active men (energy expended in physical activity > 300 kcal/day) compared with active men (energy expended in physical activity < 300 kcal/day).
CONCLUSIONS
Regular daily physical activity in individuals with a family history of CHD could be useful for controlling Lp(a) levels.
目的
本研究根据个体是否有冠心病（CHD）家族史，评估体力活动与血清脂蛋白(a)[Lp(a)]水平之间的关联。
方法
测量了332名年龄在20至60岁之间的健康西班牙男性的Lp(a)水平。评估了体力活动和冠心病家族史。
结果
对于有冠心病家族史的男性，与活动量较小的男性（体力活动消耗能量<300千卡/天）相比，活动量非常大的男性（体力活动消耗能量>300千卡/天）Lp(a)水平高于中位数的比值比为0.13（95%置信区间=0.03,0.50）。
结论
有冠心病家族史的个体进行规律的日常体力活动可能有助于控制Lp(a)水平。
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