Davies G J, Dettmar P W, Hoare R C
Nutrition Research Centre, South Bank University, London.
J R Soc Promot Health. 1998 Oct;118(5):267-71. doi: 10.1177/146642409811800511.
Frequency of defaecation, faecal form, straining at the start and end of defaecation, feelings of incomplete evacuation of faeces and urgency of defaecation were recorded in 69 healthy volunteers during three distinct 28-day study phases: pre-treatment, treatment with ispaghula husk and post-treatment. During treatment there was a significant increase (P < 0.001) in stool frequency and significant decreases in straining at the start (P < 0.001) and end (P < 0.001) of defaecation and in feelings of incomplete evacuation (P < 0.001). There was evidence of a beneficial residual effect after treatment had stopped. There are indications that ispaghula husk (Fybogel Orange) is of benefit in relieving constipation symptoms in apparently healthy people.
在三个不同的为期28天的研究阶段,即治疗前、使用卵叶车前草种子外壳治疗期间和治疗后,对69名健康志愿者的排便频率、粪便形态、排便开始和结束时的用力情况、排便不尽感和排便紧迫感进行了记录。治疗期间,大便频率显著增加(P < 0.001),排便开始时(P < 0.001)和结束时(P < 0.001)的用力情况以及排便不尽感显著降低(P < 0.001)。有证据表明在治疗停止后存在有益的残留效应。有迹象表明卵叶车前草种子外壳(Fybogel Orange)对缓解明显健康人群的便秘症状有益。