Evans K, Tyrer P, Catalan J, Schmidt U, Davidson K, Dent J, Tata P, Thornton S, Barber J, Thompson S
Department of Psychiatry, Imperial College School of Medicine, Chelsea and Westminister Hospital, London.
Psychol Med. 1999 Jan;29(1):19-25. doi: 10.1017/s003329179800765x.
The treatment of deliberate self-harm (parasuicide) remains limited in efficacy. Despite a range of psychosocial, educational and pharmacological interventions only one approach, dialectical behaviour therapy, a form of cognitive-behaviour therapy (CBT), has been shown to reduce repeat episodes, but this is lengthy and intensive and difficult to extrapolate to busy clinical practice. We investigated the effectiveness of a new manual-based treatment varying from bibliotherapy (six self-help booklets) alone to six sessions of cognitive therapy linked to the booklets, which contained elements of dialectical behaviour therapy.
Thirty-four patients, aged between 16 and 50, seen after an episode of deliberate self-harm, with personality disturbance within the flamboyant cluster and a previous parasuicide episode within the past 12 months, were randomly assigned to treatment with manual-assisted cognitive-behaviour therapy (MACT N = 18) or treatment as usual (TAU N = 16). Assessment of clinical symptoms and social function were made at baseline and repeated by an independent assessor masked to treatment allocation at 6 months. The number and rate of all parasuicide attempts, time to next episode and costs of care were also determined.
Thirty-two patients (18 MACT; 14 TAU) were seen at follow-up and 10 patients in each group (56% MACT and 71% TAU) had a suicidal act during the 6 months. The rate of suicidal acts per month was lower with MACT (median 0.17/month MACT; 0.37/month TAU; P = 0.11) and self-rated depressive symptoms also improved (P = 0.03). The treatment involved a mean of 2.7 sessions and the observed average cost of care was 46% less with MACT (P = 0.22).
Although limited by the small sample, the results of this pilot study suggest that this new form of cognitive-behaviour therapy is promising in its efficacy and feasible in clinical practice.
蓄意自伤(准自杀)的治疗效果仍然有限。尽管有一系列心理社会、教育和药物干预措施,但只有一种方法,即辩证行为疗法(一种认知行为疗法形式)已被证明可减少复发,但该疗法耗时且密集,难以推广至繁忙的临床实践中。我们研究了一种新的基于手册的治疗方法的有效性,该方法从单独的自助疗法(六本自助手册)到与手册相关的六次认知疗法,其中包含辩证行为疗法的元素。
34名年龄在16至50岁之间、在蓄意自伤发作后就诊、具有浮夸型人格障碍且在过去12个月内有过一次准自杀发作的患者,被随机分配接受手册辅助认知行为疗法(MACT,n = 18)或常规治疗(TAU,n = 16)。在基线时对临床症状和社会功能进行评估,并由对治疗分配不知情的独立评估者在6个月时重复评估。还确定了所有准自杀未遂的次数和发生率、下次发作的时间以及护理费用。
随访时见到32名患者(18名接受MACT;14名接受TAU),每组中有10名患者(MACT组为56%,TAU组为71%)在6个月内有自杀行为。MACT组每月的自杀行为发生率较低(MACT组中位数为0.17/月;TAU组为0.37/月;P = 0.11),且自评抑郁症状也有所改善(P = 0.03)。该治疗平均涉及2.7次疗程,MACT组观察到的平均护理费用低46%(P = (此处原文有误,应为P = 0.022))。
尽管受样本量小的限制,但这项初步研究的结果表明,这种新形式的认知行为疗法在疗效方面很有前景,且在临床实践中可行。