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无错误学习与记忆受损精神分裂症患者的认知康复

Errorless learning and the cognitive rehabilitation of memory-impaired schizophrenic patients.

作者信息

O'Carroll R E, Russell H H, Lawrie S M, Johnstone E C

机构信息

Department of Psychology, University of Stirling.

出版信息

Psychol Med. 1999 Jan;29(1):105-12. doi: 10.1017/s0033291798007673.

Abstract

BACKGROUND

In recent years, evidence has accumulated that a significant proportion of schizophrenic patients have severe memory impairment, which cannot be attributed to the effects of medication, chronicity or institutionalization. Our group has demonstrated that memory impairment is associated with poor psychosocial outcome and treatment resistance. Work on the classical amnesic syndrome has suggested that memory training is facilitated by adopting an 'errorless learning' approach, where subjects do not experience failure during learning. This is based on the theory that the preserved implicit memory of amnesic patients results in implicitly remembered incorrect responses interfering with target items, in the absence of a functioning explicit memory system to allow differentiation.

METHOD

We compared three groups of subjects, memory-impaired schizophrenic patients, memory unimpaired schizophrenic patients and healthy controls.

RESULTS

An errorless learning approach conferred a significant advantage on the memory-impaired schizophrenic group, bringing their performance up to the level of both control groups. In contrast, adopting a traditional trial and error, or errorful approach resulted in markedly impaired performance in the memory-impaired schizophrenic group only.

CONCLUSIONS

We conclude that errorless learning approaches may be worthy of further evaluation in the cognitive rehabilitation of memory-impaired schizophrenic patients.

摘要

背景

近年来,越来越多的证据表明,相当一部分精神分裂症患者存在严重的记忆障碍,这不能归因于药物作用、病程或住院治疗。我们的研究小组已经证明,记忆障碍与不良的心理社会结局和治疗抵抗有关。对经典遗忘综合征的研究表明,采用“无错误学习”方法有助于记忆训练,即受试者在学习过程中不会经历失败。这一方法基于这样的理论:在缺乏正常运作的外显记忆系统以进行区分的情况下,遗忘症患者保留的内隐记忆会导致内隐记忆的错误反应干扰目标项目。

方法

我们比较了三组受试者,即记忆受损的精神分裂症患者、记忆未受损的精神分裂症患者和健康对照组。

结果

无错误学习方法给记忆受损的精神分裂症患者组带来了显著优势,使其表现提升至两个对照组的水平。相比之下,采用传统的试错或有错误的方法仅导致记忆受损的精神分裂症患者组的表现明显受损。

结论

我们得出结论,无错误学习方法可能值得在记忆受损的精神分裂症患者的认知康复中进行进一步评估。

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