Malmros H
Acta Biol Med Ger. 1976;35(8-9):1151-8.
A series of photomicrographs shows that deposits of cholesterol crystals in the walls of arteries as well as in other tissues have a strong irritative effect on collagen tissue. This process is probably the very cause of the atherosclerotic plaque. Cholesterol deposits are especially abundant in hypercholesterolemia. This may be due to various factors, the most important of which is a faulty diet containing too much saturated fat. Replacement of such fat by polyunsaturated fat will lower the blood cholesterol level. From preventive point of view, it would appear advisable to change the dietary habits of the entire population in countries with a high frequency of atherosclerotic vascular diseases.
一系列显微照片显示，动脉壁以及其他组织中的胆固醇晶体沉积物对胶原组织有强烈的刺激作用。这个过程可能正是动脉粥样硬化斑块形成的原因。胆固醇沉积在高胆固醇血症中尤为丰富。这可能是由于多种因素，其中最重要的是含有过多饱和脂肪的不良饮食。用多不饱和脂肪替代此类脂肪会降低血液胆固醇水平。从预防的角度来看，在动脉粥样硬化性血管疾病高发国家，改变全体人群的饮食习惯似乎是可取的。
