Snyder A J, Rosenberg G, Pierce W S
Department of Surgery, Pennsylvania State University, Hershey 17033, USA.
Artif Organs. 1992 Apr;16(2):189-94. doi: 10.1111/j.1525-1594.1992.tb00292.x.
An artificial heart should be controlled in a noninvasive fashion; the presence of the control system should pose no risk to the patient. Ideally, much of the control function would be attained passively, by designing the pumps and energy converter so that they naturally respond in an appropriate manner to changes in the circulation. We present methods of controlling both left-right output balance and providing response to changing demands for blood flow for a class of total artificial hearts with implanted energy converters. Our balance control actively maintains left-right balance, but does so in concert with the natural response of the pumps to changes in filling pressures. Cardiac output (CO) can be made to be sensitive to right atrial pressure, but peripheral resistance is our usual cue. Alternative means of determining the correct cardiac output are discussed.
人工心脏应以非侵入性方式进行控制；控制系统的存在不应给患者带来风险。理想情况下，通过设计泵和能量转换器，使它们能以适当方式自然地响应循环系统的变化，大部分控制功能可以被动实现。我们提出了控制一类带有植入式能量转换器的全人工心脏左右输出平衡以及对不断变化的血流需求做出响应的方法。我们的平衡控制能积极维持左右平衡，且与泵对充盈压变化的自然响应协同进行。心输出量（CO）可以对右心房压力敏感，但我们通常以体循环阻力作为提示。文中还讨论了确定正确心输出量的其他方法。
