Fukushima S, Inoue T, Inoue T, Ozeki S
Department of Radiation Oncology, Osaka University Medical School, Japan.
Int J Radiat Oncol Biol Phys. 1999 Feb 1;43(3):597-600. doi: 10.1016/s0360-3016(98)00431-3.
Pterygium are triangular growths of fibrovascular tissue of the bulbar conjunctiva that ultimately cause visual disturbances. Surgical removal is the initial treatment of choice for pterygium, but the recurrence rate after excision alone is 20-40%. The purpose of this paper is to reaffirm the effectiveness of postoperative irradiation with a 90Sr eye applicator.
From 1993 to 1996, 361 patients (393 lesions) were treated with 90Sr postoperative radiation therapy. Forty-five lesions were recurrent cases. All cases had been excised using the "bare sclera" method. Postoperative radiation performed within 48 h after surgery received radiation doses of 30 Gy, the others received doses of 35 Gy, using the 90Sr eye applicator.
Thirty-four (8.6%) of the 393 lesions recurred. The overall 1-year local control rate was 93.7%. Seventy-one percent of the recurrent cases were noticed within 1.5 years after treatment. The multivariate analysis for total cases demonstrated that sex, age, prior treatment, and duration of pterygium affected the overall local control rate. No complications from this treatment have been observed.
It was reconfirmed that postoperative irradiation was effective in preventing local recurrence after surgical removal of pterygium.
翼状胬肉是球结膜纤维血管组织的三角形增生，最终会导致视力障碍。手术切除是翼状胬肉的首选初始治疗方法，但单纯切除后的复发率为20%-40%。本文的目的是再次证实使用90锶眼部敷贴器进行术后照射的有效性。
1993年至1996年，361例患者（393处病变）接受了90锶术后放射治疗。45处病变为复发病例。所有病例均采用“裸巩膜”法切除。术后48小时内进行的放射治疗，使用90锶眼部敷贴器，放射剂量为30戈瑞，其他病例接受35戈瑞的剂量。
393处病变中有34处（8.6%）复发。总体1年局部控制率为93.7%。71%的复发病例在治疗后1.5年内被发现。对所有病例的多因素分析表明，性别、年龄、既往治疗情况和翼状胬肉病程影响总体局部控制率。未观察到该治疗的并发症。
再次证实术后照射对预防翼状胬肉手术切除后的局部复发有效。
