伴有谷氨酸脱羧酶自身抗体的小脑性共济失调
Cerebellar ataxia with glutamic acid decarboxylase autoantibodies.
作者信息
Abele M, Weller M, Mescheriakov S, Bürk K, Dichgans J, Klockgether T
机构信息
Department of Neurology, University of Tübingen, Germany.
出版信息
Neurology. 1999 Mar 10;52(4):857-9. doi: 10.1212/wnl.52.4.857.
PMID:10078741
Abstract
Degenerative cerebellar ataxia with autoantibodies against glutamic acid decarboxylase (GAD) is a rare disorder and may represent a subset of ataxias previously classified as idiopathic. The authors report a patient with progressive cerebellar ataxia, insulin-dependent diabetes mellitus, and GAD antibodies who responded to i.v. immunoglobulins.
摘要
伴有抗谷氨酸脱羧酶（GAD）自身抗体的退行性小脑共济失调是一种罕见疾病，可能代表了先前归类为特发性共济失调的一个亚型。作者报告了一名患有进行性小脑共济失调、胰岛素依赖型糖尿病且存在GAD抗体的患者，该患者对静脉注射免疫球蛋白有反应。
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