Torbey C F, Achkar E, Rice T W, Baker M, Richter J E
Department of Gastroenterology, The Cleveland Clinic Foundation, Ohio 44195, USA.
J Clin Gastroenterol. 1999 Mar;28(2):125-30. doi: 10.1097/00004836-199903000-00008.
Treatment of achalasia includes pneumatic dilation (PD) and surgical myotomy (SM). Success rates range from 32% to 98% and are mostly based on symptomatic response. Our aims were to determine the long-term outcome of patients treated for achalasia and the adequacy of long-term follow-up. Patients treated with PD or SM between 1986 and 1990 were contacted by telephone after a minimum of 4 years after treatment, and asked about symptoms and need for retreatment since their discharge from our institution. Symptomatic response was classified as excellent/good or fair/poor using the Vantrappen score. Treatment was deemed a failure if patients were symptomatic on callback, needed retreatment, technical problems occurred during PD, or perforation occurred. Forty-seven PD patients and 15 SM patients were studied. There were no significant differences in clinical parameters between groups. Median time to callback was 82 and 73 months, respectively. Failure rates were high, respectively 74% and 67%. Importantly, 38% of PD and 33% of SM patients failed to seek help despite symptom recurrence. Achalasia treatment failures are higher than anticipated. This may be because of the lack of routine follow-up as well as patients' failure to seek help when symptoms recur. Achalasia patients need closer follow-up and may benefit from early intervention based on objective tests rather than symptoms alone.
贲门失弛缓症的治疗方法包括气囊扩张术(PD)和手术肌切开术(SM)。成功率在32%至98%之间,且大多基于症状缓解情况。我们的目的是确定接受贲门失弛缓症治疗患者的长期预后以及长期随访的充分性。在1986年至1990年间接受PD或SM治疗的患者,在治疗后至少4年通过电话联系,并询问自出院以来的症状及再次治疗的需求。使用万特拉彭评分将症状缓解情况分为优/良或中/差。如果患者在回访时有症状、需要再次治疗、在PD过程中出现技术问题或发生穿孔,则认为治疗失败。对47例接受PD治疗的患者和15例接受SM治疗的患者进行了研究。两组之间的临床参数无显著差异。回访的中位时间分别为82个月和73个月。失败率较高,分别为74%和67%。重要的是,38%接受PD治疗的患者和33%接受SM治疗的患者尽管症状复发但未寻求帮助。贲门失弛缓症的治疗失败率高于预期。这可能是由于缺乏常规随访以及患者在症状复发时未寻求帮助。贲门失弛缓症患者需要更密切的随访,且可能受益于基于客观检查而非仅基于症状的早期干预。