Andreeva S G, Merkulova M I, Shuvaeva T M, Novoselov V I, Peshenko I V, Novoselov S V, Fesenko E E, Lipkin V M
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Bioorg Khim. 1998 Nov;24(11):816-21.
Clone lambda a26.1 isolated from rat olfactory epithelium contains a full-length 28-kDa protein cDNA (1414 b.p.). The reconstructed protein sequence comprises 223 aa with a calculated molecular mass of 24,630 Da. A substantial homology was revealed between the amino acid sequence of the 28-kDa protein and those of thiol-specific antioxidants (peroxiredoxines). The 28-kDa protein belongs to the 1 Cys-subfamily of peroxiredoxines and is the first member of peroxiredoxines identified in the olfactory epithelium.
从大鼠嗅觉上皮中分离出的λa26.1克隆含有一个全长28 kDa蛋白的cDNA(1414个碱基对)。重建的蛋白质序列由223个氨基酸组成,计算分子量为24,630 Da。28 kDa蛋白的氨基酸序列与硫醇特异性抗氧化剂(过氧化物酶)的氨基酸序列之间显示出高度同源性。28 kDa蛋白属于过氧化物酶的1个半胱氨酸亚家族,是在嗅觉上皮中鉴定出的第一个过氧化物酶成员。