Greene J N, Poblete S J, Krieff D
Division of Infectious and Tropical Diseases, University of South Florida College of Medicine, Tampa, USA.
Chest Surg Clin N Am. 1999 Feb;9(1):39-61, vii-viii.
The virulent microorganisms that we try to contain with new antimicrobial agents quickly find the gap in our defenses and exploit it. Resistance to all available antibiotics at the same time, however, rarely occurs. The authors report the most current antimicrobials used as monotherapy or in combination to successfully treat the more resistant pathogens. The higher mortality and subsequent cost to treat these infections are reviewed.
我们试图用新型抗菌药物控制的致病微生物很快就能找到我们防御体系中的漏洞并加以利用。然而，同时对所有可用抗生素产生耐药性的情况很少发生。作者报告了目前用作单一疗法或联合疗法以成功治疗耐药性更强的病原体的最新抗菌药物。文中还综述了治疗这些感染时更高的死亡率及后续成本。
