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异恶酰胺与阿司匹林或右丙氧芬联合使用的抗炎活性。

Anti-inflammatory activity of isoxicam in combination with aspirin or D-propoxyphene.

作者信息

DiPasquale G, Rassaert C, Welaj P, Tripp L

出版信息

Agents Actions. 1976 Nov;6(6):748-54. doi: 10.1007/BF02026098.

DOI:10.1007/BF02026098
PMID:1008020
Abstract

Unlike several arylacetic acid derivatives (indomethacin, fenoprofen, ibuprofen, flurbiprofen and naproxen), the anti-arthritic activity of isoxicam is not reduced in the adjuvant-induced polyarthritis assay by the concomitant administration of aspirin or D-propoxyphene.

摘要

与几种芳基乙酸衍生物(吲哚美辛、非诺洛芬、布洛芬、氟比洛芬和萘普生)不同,在佐剂诱导的多关节炎试验中,同时给予阿司匹林或右丙氧芬不会降低异恶酰胺的抗关节炎活性。

相似文献

1
Anti-inflammatory activity of isoxicam in combination with aspirin or D-propoxyphene.异恶酰胺与阿司匹林或右丙氧芬联合使用的抗炎活性。
Agents Actions. 1976 Nov;6(6):748-54. doi: 10.1007/BF02026098.
2
Effects of multiple treatments of isoxicam on organ weights and serum SGPT, AP, and BUN in adjuvant-induced polyarthritic rats.异丁苯丙酸多次治疗对佐剂诱导的多关节炎大鼠器官重量及血清谷丙转氨酶、碱性磷酸酶和尿素氮的影响。
Res Commun Chem Pathol Pharmacol. 1978 Mar;19(3):529-32.
3
A multicenter study for analgesia involving fenoprofen, propoxyphene [alone or in combination] with placebo and aspirin controls in postpartum pain.一项多中心研究,在产后疼痛中使用非诺洛芬、丙氧芬(单独使用或联合使用)与安慰剂及阿司匹林对照进行镇痛。
J Med. 1979;10(1-2):65-98.
4
A comparative analgesic study of propoxyphene, fenoprofen, the combination of propoxyphene and fenoprofen, aspirin, and placebo.丙氧芬、非诺洛芬、丙氧芬与非诺洛芬组合、阿司匹林及安慰剂的镇痛比较研究。
J Clin Pharmacol. 1978 Nov-Dec;18(11-12):556-63. doi: 10.1002/j.1552-4604.1978.tb01585.x.
5
Isoxicam and related 4-hydroxy-N-isoxazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides. Potent nonsteroidal antiinflammatory agents.
J Med Chem. 1982 Jan;25(1):12-8. doi: 10.1021/jm00343a003.
6
The anti=inflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide).异恶丙嗪(4-羟基-2-甲基-N-(5-甲基-3-异恶唑基-2H-1,2-苯并噻嗪-3-甲酰胺1,1-二氧化物)的抗炎特性。 (注:原文中“anti=inflammatory”拼写有误,正确应为“anti-inflammatory”)
Agents Actions. 1975 Aug;5(3):256-63. doi: 10.1007/BF02026440.
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The analgesic activity of propoxyphene napsylate with and without aspirin.含与不含阿司匹林的萘磺酸丙氧芬的镇痛活性。
J Clin Pharmacol New Drugs. 1971 Jul-Aug;11(4):310-7.
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Update on ibuprofen for rheumatoid arthritis.布洛芬治疗类风湿性关节炎的最新进展。
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Evaluation of the safety of isoxicam.异恶酰胺安全性评估。
Am J Med. 1985 Oct 18;79(4B):28-32. doi: 10.1016/0002-9343(85)90178-0.
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Nonsteroidal anti-inflammatory agents. A review of the literature.非甾体抗炎药。文献综述。
J Am Podiatr Med Assoc. 1985 Oct;75(10):517-22. doi: 10.7547/87507315-75-10-517.

引用本文的文献

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Synergism between subthreshold doses of phenylbutazone and prednisolone in rat hind-paw carrageenan edema.苯丁酮酸和泼尼松龙阈下剂量对大鼠后爪角叉菜胶性水肿的协同作用。
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本文引用的文献

1
Comparative effects of salicylic acid, phenylbutazone, probenecid and other anions on the metabolism, distribution and excretion of indomethacin by rats.水杨酸、保泰松、丙磺舒及其他阴离子对大鼠体内吲哚美辛代谢、分布和排泄的比较作用。
Biochem Pharmacol. 1970 May;19(5):1591-600. doi: 10.1016/0006-2952(70)90147-4.
2
Interaction between aspirin and indomethacin in the treatment of rheumatoid arthritis.
Med J Aust. 1970 Jul 18;2(3):127-9. doi: 10.5694/j.1326-5377.1970.tb87342.x.
3
Interactions of anti-inflammatory drugs in carrageenan-induced foot edema of the rat.抗炎药物在角叉菜胶诱导的大鼠足肿胀中的相互作用。
J Pharmacol Exp Ther. 1970 Apr;172(2):423-5.
4
Interactions of drugs with aspirin.药物与阿司匹林的相互作用。
J Am Pharm Assoc. 1970 Feb;10(2):83-5. doi: 10.1016/s0003-0465(16)31124-7.
5
Interactions of spironolactone and hydrochlorothiazide with aspirin in the rat and dog.
J Pharmacol Exp Ther. 1972 Jan;180(1):1-5.
6
[Experimental results of combinations of nonsteroid anti-inflammatory agents in acute and chronic inflammation].
Rev Rhum Mal Osteoartic. 1974 Mar;41(3):163-71.
7
Naproxen-aspirin interactions in man.萘普生与阿司匹林在人体中的相互作用。
Clin Pharmacol Ther. 1974 Apr;15(4):374-9. doi: 10.1002/cpt1974154374.
8
Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat.阿司匹林、吲哚美辛及其他药物在佐剂诱导的大鼠关节炎中的相互作用。
J Pharmacol Exp Ther. 1973 Nov;187(2):400-14.
9
The anti-inflammatory effects of 4-hydroxy-2-methyl-3-phenylcarbamoyl-2H-1,2-benzothiazine-1,1-dioxide (W7477).
Arch Int Pharmacodyn Ther. 1973 May;203(1):92-100.
10
Drug interactions.药物相互作用。
Med Clin North Am. 1974 Sep;58(5):965-75. doi: 10.1016/s0025-7125(16)32093-4.