Hannerz J, Ericson K, Bro Skejø H P
Department of Neurology, Karolinska Hospital, Stockholm, Sweden.
Acta Radiol. 1999 Mar;40(2):135-41. doi: 10.3109/02841859909177728.
To study frequency and extent of meningeal enhancement in patients with and without post-lumbar puncture headache (PLPH) with cerebral MR with Gd-DTPA.
Ten consecutive patients with PLPH and 9 consecutive patients without PLPH were included in the study. Nine of the PLPH patients were reinvestigated when the PLPH was over and all non-PLPH patients during the week after the lumbar puncture.
Eight of the 9 patients with PLPH showed more enhancement of meningeal structures during PLPH than when PLPH had disappeared. The differences were slight in 5, more marked in 2, and pronounced in 1 patient. The 9th patient showed no change at all. In the 9 patients without PLPH, there was mainly slight enhancement before lumbar puncture and no change in enhancement after lumbar puncture as compared with before.
PLPH is related to increased Gd-DTPA enhancement of the meninges, although the increase in enhancement during PLPH is minor in most cases. Pronounced enhancement of the meninges after lumbar puncture may predict long duration of the PLPH.
利用钆喷酸葡胺（Gd-DTPA）增强脑磁共振成像（MR），研究有或无腰穿后头痛（PLPH）患者硬脑膜强化的频率和程度。
本研究纳入了10例连续的PLPH患者和9例连续的无PLPH患者。9例PLPH患者在PLPH结束后再次接受检查，所有非PLPH患者在腰穿后一周内接受检查。
9例PLPH患者中有8例显示，PLPH期间脑膜结构的强化比PLPH消失时更明显。5例差异轻微，2例差异更显著，1例差异明显。第9例患者无任何变化。9例无PLPH患者中，腰穿前主要为轻微强化，与腰穿前相比，腰穿后强化无变化。
PLPH与脑膜钆喷酸葡胺强化增加有关，尽管在大多数情况下，PLPH期间强化增加较小。腰穿后脑膜明显强化可能预示PLPH持续时间较长。
