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患有共病性癫痫的自闭症患者:与病毒感染的可能关联。

Autistic subjects with comorbid epilepsy: a possible association with viral infections.

作者信息

Barak Y, Kimhi R, Stein D, Gutman J, Weizman A

机构信息

Abarbanel Mental Health Center, Bat-Yam, Israel.

出版信息

Child Psychiatry Hum Dev. 1999 Spring;29(3):245-51. doi: 10.1023/a:1022669125423.

DOI:10.1023/a:1022669125423
PMID:10080966
Abstract

This study evaluates the comorbidity of epilepsy as a variable supporting a viral hypothesis in Autism. Data covering a 30-year period (1960-1989), including general population live births, autistic births, and incidence of viral encephalitis and viral meningitis, were collected for Israel. 290 autistic births were evaluated. The annual birth pattern of subjects with comorbid epilepsy fit the seasonality of viral meningitis. These findings support the role of viral C.N.S. infections in the causality of this disorder.

摘要

本研究评估癫痫共病作为支持自闭症病毒假说的一个变量。收集了以色列30年期间(1960 - 1989年)的数据,包括普通人群活产、自闭症活产以及病毒性脑炎和病毒性脑膜炎的发病率。对290例自闭症活产进行了评估。合并癫痫的受试者的年度出生模式符合病毒性脑膜炎的季节性。这些发现支持病毒性中枢神经系统感染在这种疾病病因中的作用。

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Autistic subjects with comorbid epilepsy: a possible association with viral infections.患有共病性癫痫的自闭症患者:与病毒感染的可能关联。
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Autistic disorder and viral infections.自闭症谱系障碍与病毒感染。

本文引用的文献

1
Psychiatric disorders in children and adolescents with mental retardation and active epilepsy.患有智力障碍和活动性癫痫的儿童及青少年的精神障碍
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Prenatal viral infection leads to pyramidal cell atrophy and macrocephaly in adulthood: implications for genesis of autism and schizophrenia.产前病毒感染导致成年期锥体细胞萎缩和巨头畸形:对自闭症和精神分裂症发生的影响。
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Season of birth and neurodevelopmental disorders: summer birth is associated with dyslexia.出生季节与神经发育障碍:夏季出生与诵读困难有关。
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Acquired reversible autistic syndrome in acute encephalopathic illness in children.儿童急性脑病性疾病中的获得性可逆性自闭症综合征
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J Neurol Neurosurg Psychiatry. 1988 Jun;51(6):753-6. doi: 10.1136/jnnp.51.6.753.