使用单克隆抗体预防流行性传染病的黏膜传播。
Using monoclonal antibodies to prevent mucosal transmission of epidemic infectious diseases.
作者信息
Zeitlin L, Cone R A, Whaley K J
机构信息
ReProtect, LLC, Baltimore, Maryland, USA.
出版信息
Emerg Infect Dis. 1999 Jan-Feb;5(1):54-64. doi: 10.3201/eid0501.990107.
Abstract
Passive immunization with antibodies has been shown to prevent a wide variety of diseases. Recent advances in monoclonal antibody technology are enabling the development of new methods for passive immunization of mucosal surfaces. Human monoclonal antibodies, produced rapidly, inexpensively, and in large quantities, may help prevent respiratory, diarrheal, and sexually transmitted diseases on a public health scale.
摘要
已证明用抗体进行被动免疫可预防多种疾病。单克隆抗体技术的最新进展使开发用于黏膜表面被动免疫的新方法成为可能。快速、廉价且大量生产的人源单克隆抗体可能有助于在公共卫生层面预防呼吸道疾病、腹泻病和性传播疾病。
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