School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
Braz J Med Biol Res. 2020 Jan 24;53(2):e8749. doi: 10.1590/1414-431X20198749. eCollection 2020.
For a long time, vaccines have been the main mode of defense and protection against several bacterial, viral, and parasitic diseases. However, the process of production and purification makes them expensive and unaffordable to many developing nations. An edible vaccine is when the antigen is expressed in the edible part of the plant. This reduces the cost of production of the vaccine because of ease of culturing. In this article, various types of edible vaccines that include algal and probiotics in addition to plants are discussed. Various diseases against which research has been carried out are also reviewed. This article focused on the conception of edible vaccines highlighting the various ways by which vaccines can be delivered.
长期以来，疫苗一直是防御和预防多种细菌、病毒和寄生虫疾病的主要手段。然而，生产和提纯的过程使得它们对许多发展中国家来说昂贵且难以负担。可食用疫苗是指抗原在植物的可食用部分表达。这降低了疫苗的生产成本，因为培养起来更容易。本文讨论了包括藻类和益生菌在内的各种可食用疫苗。还回顾了针对各种已开展研究的疾病。本文重点介绍了可食用疫苗的概念，强调了疫苗可以通过各种方式进行输送。
