Nakao K, Sato T, Shirai W, Matsuo K
Department of Veterinary Pathology, College of Bioresourse Sciences, Nihon University, Kanagawa, Japan.
J Vet Med Sci. 1999 Feb;61(2):191-3. doi: 10.1292/jvms.61.191.
A malignant basal cell tumor was found in the skin of the abdomen of a female Djungarian hamster of unknown age and weighing 40 g. Histologically, the tumor mass was composed of cells resembling the basal cells of the epidermis, and these cells exhibited solid type proliferation. In the tumor tissue and necrotic foci, horn cysts were observed. Immunohistochemically, cytokeratin was present in the tumor cells and horncysts. By electron microscopic examination, the tumor cells had scanty cell organelles and a few desmozomes. This paper describes a rare malignant basal cell tumor in a Djungarian hamster.
在一只年龄不详、体重40克的雌性侏儒仓鼠腹部皮肤发现了一个恶性基底细胞瘤。组织学上，肿瘤块由类似于表皮基底细胞的细胞组成，这些细胞呈实性增殖。在肿瘤组织和坏死灶中观察到角囊肿。免疫组织化学检查显示，肿瘤细胞和角囊肿中存在细胞角蛋白。通过电子显微镜检查，肿瘤细胞细胞器稀少，有少量桥粒。本文描述了一只侏儒仓鼠中罕见的恶性基底细胞瘤。
