Málek F, Málková J, Pokorný R
First Medical Department, Third Medical Faculty, Charles University, Prague, Czech Republic.
Cent Eur J Public Health. 1999 Feb;7(1):3-7.
In 28 neonates born by spontaneous delivery to healthy mothers with a normal course of gestation venous umbilical blood was examined to assess the immunoreactive insulin concentration. Moreover, the birth weight of the neonates was recorded, the weight increment of the mother during pregnancy and the body mass index at the end of gestation. By means of a questionnaire and the computer programme Progana the dietary intake of the mothers at the end of pregnancy was assessed and compared with recommended allowances. The assembled data were evaluated statistically by assessment of the correlation coefficient. The investigation revealed that the birth weight of the neonates in the group does not correlate with the immunoreactive insulin concentration in umbilical venous blood. Although the dietary intake of the mothers at the end of pregnancy is not ideal (fat and cholesterol intake predominates over carbohydrate and protein intake), it does not correlate with the birth weight of the neonates nor with the immunoreactive insulin concentration in umbilical venous blood. From these results the conclusion is drawn that neonates with a low birth weight do not have a higher plasma insulin concentration after delivery and that the mother's diet at the end of pregnancy does not influence the birth weight and insulin level in neonates.
对28例由健康母亲自然分娩的新生儿进行研究，这些母亲孕期过程正常，检测其脐静脉血以评估免疫反应性胰岛素浓度。此外，记录新生儿的出生体重、母亲孕期体重增加情况以及妊娠末期的体重指数。通过问卷调查和计算机程序Progana评估母亲妊娠末期的饮食摄入量，并与推荐摄入量进行比较。对收集的数据通过评估相关系数进行统计学评估。调查显示，该组新生儿的出生体重与脐静脉血中免疫反应性胰岛素浓度无关。尽管母亲妊娠末期的饮食摄入量不理想（脂肪和胆固醇摄入量高于碳水化合物和蛋白质摄入量），但它与新生儿的出生体重以及脐静脉血中免疫反应性胰岛素浓度均无关。从这些结果得出结论，低出生体重的新生儿出生后血浆胰岛素浓度并不更高，且母亲妊娠末期的饮食不会影响新生儿的出生体重和胰岛素水平。
