Enzymatic methods for mutation scanning.
作者信息
Taylor G R, Deeble J
机构信息
DNA Laboratory, St. James's University Hospital, Leeds, UK.
出版信息
Genet Anal. 1999 Feb;14(5-6):181-6. doi: 10.1016/s1050-3862(98)00029-1.
Abstract
Enzymatic methods for mutation scanning still lack the sensitivity and specificity of the chemical cleavage of mismatch method. However developments in our understanding of the mismatch recognition process should lead to improvements. Several promising candidates exist with potential for more specific and sensitive mutation detection.
摘要
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