钇90氢氧化铁胶体和金198胶体注入膝关节后的分布情况。
Distribution of yttrium 90 ferric hydroxide colloid and gold 198 colloid after injection into knee.
作者信息
Williams E D, Caughey D E, Hurley P J, John M B
出版信息
Ann Rheum Dis. 1976 Dec;35(6):516-20. doi: 10.1136/ard.35.6.516.
Abstract
Thirteen knees were injected with yttrium 90(90Y) ferric hydroxide colloid, and 12 with gold 198(198Au) colloid for treatment of persistent synovitis. Retention in the knee and uptake in lymph nodes and liver were measured by a quantitative scanning technique. There was no significant difference in the retention in the knee of the two different colloids. A tendency towards higher lymph node uptake was observed with 198Au compared with 90y. The inflammatory activity of the knee at the time of treatment may have influenced the subsequent lymph node uptake of 198Au, but not that of the 90Y, nor the overall leakage of either from the knee. 90Yferric hydroxide colloid was retained in the treated knee at least as well as other colloids which have been used for this purpose.
摘要
为治疗持续性滑膜炎，对13个膝关节注射了钇90（90Y）氢氧化铁胶体，对12个膝关节注射了金198（198Au）胶体。采用定量扫描技术测量胶体在膝关节内的滞留情况以及在淋巴结和肝脏中的摄取情况。两种不同胶体在膝关节内的滞留情况无显著差异。与90Y相比，观察到198Au在淋巴结中的摄取有升高趋势。治疗时膝关节的炎症活动可能影响了随后198Au在淋巴结中的摄取，但未影响90Y在淋巴结中的摄取，也未影响二者从膝关节的总体渗漏情况。90Y氢氧化铁胶体在治疗后的膝关节内的滞留情况至少与用于此目的的其他胶体一样好。
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