Saika T, Manabe D, Suyama B
Department of Urology, Mitoyo General Hospital.
Hinyokika Kiyo. 1999 Jan;45(1):19-23.
We compared the clinical and functional results of radical cystectomy and urinary reconstructions performed on 19 elderly bladder cancer patients over 75 years old to those on 22 younger patients to determine whether age was one of the critical points for the application of this type of surgery. Between January 1992 and January 1998, bladder substitution was performed after cystectomy using either the Hautmann, Studer or Reddy procedure in 9 of the 19 elderly patients. Urinary diversion was performed after cystectomy using ileal conduit and ureterocutaneostomy procedures in the rest of the patients. On the other hand, bladder substitutions were performed in 11; urinary diversions with continent urinary reservoir in 6 and with ileal conduit in 4 of the 22 younger patients. Neither prolongation of the operation time, nor increase in the amount of bleeding or prolongation of the post-operative hospitalization period was observed in any procedure used for elderly patients in comparison with younger ones. In elderly patients, the average operation time of radical cystectomy with bladder substitution was slightly longer than that of total cystectomy with ileal conduit or ureterocutaneostomy. The post-operative hospitalization period in the case of bladder substitution was similar to that for ileal conduit and ureterocutaneostomy with the difference of only 5 days on average. There were no peri-operative deaths, and early post-operative complications were observed in 3 of 9 cases of the bladder substitution, in 4 of 10 cases of ileal conduit or ureterocutaneostomy. Five cases of bladder substitution maintained their comfortable voiding urine comfortably, while 4 had dysuria and/or urinary incontinence. Over all, late complications occurred in 10 of the elderly patients. The rate and types of complications in the elderly patients were not different from those in the younger patients. The cause-specific survival rate and overall survival rates of the elderly patients were similar to those of the younger patients. In conclusion, indication of cystectomy and selection of urinary reconstruction procedure are not dependent on patient's age, Orthotopic urinary reservoir was found to be useful for even an elderly patient.
我们将19例75岁以上老年膀胱癌患者接受根治性膀胱切除术及尿路重建的临床和功能结果与22例年轻患者的结果进行比较,以确定年龄是否为应用此类手术的关键因素之一。1992年1月至1998年1月期间,19例老年患者中有9例在膀胱切除术后采用豪特曼、施图德或雷迪手术进行膀胱替代。其余患者在膀胱切除术后采用回肠导管和输尿管皮肤造口术进行尿流改道。另一方面,22例年轻患者中有11例行膀胱替代术;6例行可控性尿流改道术,4例行回肠导管尿流改道术。与年轻患者相比,老年患者所采用的任何手术方式均未观察到手术时间延长、出血量增加或术后住院时间延长。在老年患者中,根治性膀胱切除并膀胱替代术的平均手术时间略长于全膀胱切除并回肠导管或输尿管皮肤造口术。膀胱替代术的术后住院时间与回肠导管和输尿管皮肤造口术相似,平均差异仅为5天。无围手术期死亡病例,膀胱替代术9例中有3例、回肠导管或输尿管皮肤造口术10例中有4例出现早期术后并发症。5例膀胱替代术患者排尿舒适,4例有排尿困难和/或尿失禁。总体而言,10例老年患者出现晚期并发症。老年患者并发症的发生率和类型与年轻患者无异。老年患者的病因特异性生存率和总生存率与年轻患者相似。总之,膀胱切除术的适应证和尿路重建手术的选择不取决于患者年龄,原位尿流改道术对老年患者同样有用。