Deliveliotis C, Papatsoris A, Chrisofos M, Dellis A, Liakouras C, Skolarikos A
Second Department of Urology, School of Medicine, University of Athens, Sismanoglio General Hospital, Athens, Greece.
Urology. 2005 Aug;66(2):299-304. doi: 10.1016/j.urology.2005.03.031.
To evaluate the efficacy and safety of the type of urinary diversion during radical cystectomy in high-risk elderly patients by comparing a modified cutaneous ureterostomy with the ileal conduit urinary diversion.
Of 481 patients who underwent radical cystectomy between 1993 and 2002, 54 individuals older than 75 years with an American Society of Anesthesiologists score of 3e, 4, or 4e were characterized as high risk. These patients were grouped according to those who underwent a modified cutaneous ureterostomy (group 1, 29 patients) and those who underwent ileal conduit urinary diversion (group 2, 25 patients). Student's t and Fisher's exact tests were used for statistical analysis.
The patients in group 2 had a longer operative time (P < 0.001), an increased need for blood transfusion (P = 0.025), an increased need for intensive care monitoring (P = 0.032), and a longer mean hospitalization time (P < 0.001) than the patients in group 1. In group 2, we recorded statistically greater rates of intraoperative complications (P = 0.035), early medical and surgical complications (P = 0.031 and P = 0.012, respectively), and late surgical complications (P = 0.004). The intraoperative, early, and late surgical complication rate was 13.7%, 24.1%, and 17.2% in group 1 and 40%, 60%, and 56% in group 2, respectively. One patient in group 2 died in the early postoperative period.
Cutaneous ureterostomy represents a simplified alternative for urinary diversion in high-risk elderly patients. It can be performed quickly, with few early and late postoperative complications compared with the ileal conduit operation.
通过比较改良皮肤输尿管造口术与回肠膀胱术式,评估高危老年患者根治性膀胱切除术中尿路改道方式的疗效和安全性。
在1993年至2002年间接受根治性膀胱切除术的481例患者中,54例年龄超过75岁、美国麻醉医师协会评分为3e、4或4e的患者被视为高危患者。这些患者根据接受改良皮肤输尿管造口术(第1组,29例患者)和接受回肠膀胱术式(第2组,25例患者)进行分组。采用Student's t检验和Fisher精确检验进行统计分析。
与第1组患者相比,第2组患者的手术时间更长(P < 0.001),输血需求增加(P = 0.025),重症监护监测需求增加(P = 0.032),平均住院时间更长(P < 0.001)。在第2组中,我们记录到术中并发症发生率(P = 0.035)、早期内科和外科并发症发生率(分别为P = 0.031和P = 0.012)以及晚期外科并发症发生率(P = 0.004)在统计学上更高。第1组的术中、早期和晚期手术并发症发生率分别为13.7%、24.1%和17.2%,第2组分别为40%、60%和56%。第2组中有1例患者在术后早期死亡。
皮肤输尿管造口术是高危老年患者尿路改道的一种简化替代方法。与回肠膀胱术相比,它可以快速完成,术后早期和晚期并发症较少。