Tashiro H, Koyanagi S, Narabayashi H, Inou T, Takeshita A
Division of Cardiology, St. Mary's Hospital, Fukuoka.
J Cardiol. 1999 Feb;33(2):75-9.
Exercise echocardiography and exercise thallium-201 (201Tl) single photon emission computed tomography (SPECT) were performed in 152 patients with suspected coronary artery disease, including 61 patients with old myocardial infarction. All patients underwent coronary arteriography, and coronary artery disease was defined as > or = 75% diameter stenosis. Digital two-dimensional echocardiography was performed before and after the treadmill exercise test, and wall motion abnormality was evaluated using quad-screen. Sensitivity and specificity for the diagnosis of coronary artery disease were similar for the 2 exercise tests (77% and 80% for echocardiography and 75%, and 83% for SPECT, respectively). Diagnoses for one-vessel disease, 2-vessel disease and 3-vessel disease were similar for echocardiography (79%, 72% and 77%, respectively) and SPECT (74%, 75% and 77%, respectively). Sensitivity for the diagnosis of ischemia at the area remote from infarct area was low for both exercise echocardiography and exercise SPECT (45% and 48%, respectively). Exercise echocardiography has comparable diagnostic value to SPECT for the detection of coronary artery disease. However, both exercise tests have limitations for the diagnosis of ischemia at the area remote from infarct area.
对152例疑似冠心病患者进行了运动超声心动图和运动铊-201(201Tl)单光子发射计算机断层扫描(SPECT)检查,其中包括61例陈旧性心肌梗死患者。所有患者均接受了冠状动脉造影,冠状动脉疾病定义为直径狭窄≥75%。在平板运动试验前后进行数字二维超声心动图检查,并使用四屏法评估室壁运动异常。两种运动试验对冠心病诊断的敏感性和特异性相似(超声心动图分别为77%和80%,SPECT分别为75%和83%)。超声心动图(分别为79%、72%和77%)和SPECT(分别为74%、75%和77%)对单支血管病变、双支血管病变和三支血管病变的诊断相似。运动超声心动图和运动SPECT对梗死区以外区域缺血诊断的敏感性均较低(分别为45%和48%)。运动超声心动图在检测冠状动脉疾病方面与SPECT具有相当的诊断价值。然而,两种运动试验在诊断梗死区以外区域缺血方面均存在局限性。