在蛋白聚糖生成中断期间软骨中的胶原蛋白合成与沉积。
Collagen synthesis and deposition in cartilage during disrupted proteoglycan production.
作者信息
Dondi P, Muir H
出版信息
Biochem J. 1976 Oct 15;160(1):117-20. doi: 10.1042/bj1600117.
Abstract
A simple system was developed to investigate in vitro the possible relationship between collagen and proteoglycan synthesis in cartilage. When production of complete proteoglycan molecules was effectively inhibited with 4-methylumbelliferyl beta-D-xyloside collagen synthesis and distribution were virtually unaffected.
摘要
开发了一个简单的系统来体外研究软骨中胶原蛋白和蛋白聚糖合成之间可能的关系。当用4-甲基伞形酮基-β-D-木糖苷有效抑制完整蛋白聚糖分子的产生时，胶原蛋白的合成和分布实际上未受影响。
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本文引用的文献
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Proc Natl Acad Sci U S A. 1974 Oct;71(10):4047-51. doi: 10.1073/pnas.71.10.4047.
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