Coelho R, Silva C, Maia A, Prata J, Barros H
Department of Psychiatry, Hospital S. João, University of Porto Medical School, Portugal.
J Psychosom Res. 1999 Jan;46(1):29-35. doi: 10.1016/s0022-3999(98)00064-6.
In a community sample of 102 Portuguese white women we evaluated the relationship between osteoporosis and indexes of psychopathology and well-being. Depressive symptoms were assessed by the Beck Depression Inventory (BDI), psychopathology by the Hopkins Symptom Checklist-90 Revised (SCL-90-R), and quality of life using the Psychological General Well-Being Index. A questionnaire comprising social, demographic, clinical, and behavioral characteristics was also used. The sample prevalence of osteoporosis was 47.1%. Women with osteoporosis presented significantly higher scores on the total BDI (16+/-9 vs. 13+/-10, p=0.045) and lower scores in the hostility (0.8+/-0.6 vs. 1.2+/-0.7, p=0.012) and phobic anxiety (1.1+/-0.8 vs. 1.5+/-0.9, p=0.041) subscales of the SCL-90-R. No differences were found regarding mean general well-being scores (62+/-17 vs. 64+/-19, p=0.665). This study showed that women with osteoporosis have significantly higher levels of depressive symptoms and a corresponding higher prevalence of depression, independent of other factors strongly associated with osteoporosis, such as age or body mass index.
在一个由102名葡萄牙白人女性组成的社区样本中，我们评估了骨质疏松症与精神病理学指标及幸福感之间的关系。通过贝克抑郁量表（BDI）评估抑郁症状，通过症状自评量表90修订版（SCL-90-R）评估精神病理学状况，并使用心理总体幸福感指数评估生活质量。还使用了一份包含社会、人口统计学、临床和行为特征的问卷。骨质疏松症的样本患病率为47.1%。患有骨质疏松症的女性在BDI总分上显著更高（16±9 vs. 13±10，p=0.045），而在SCL-90-R的敌对性（0.8±0.6 vs. 1.2±0.7，p=0.012）和恐惧焦虑（1.1±0.8 vs. 1.5±0.9，p=0.041）子量表上得分更低。在总体幸福感平均得分方面未发现差异（62±17 vs. 64±19，p=0.665）。这项研究表明，患有骨质疏松症的女性抑郁症状水平显著更高，抑郁症患病率相应更高，且独立于与骨质疏松症密切相关的其他因素，如年龄或体重指数。
