含2'-脱氧-N6-甲氧基腺苷的d(CGCGmo6AATCCGCG) DNA十二聚体的结晶及初步分析：不同湿度下晶体堆积的变化
Crystallization and preliminary analysis of a DNA dodecamer of d(CGCGmo6AATCCGCG) containing 2'-deoxy-N6-methoxyadenosine: change in crystal packing with different humidity.
作者信息
Chatake T, Sunami T, Ono A, Ueno Y, Matsuda A, Takenaka A
机构信息
Department of Life Sciences, Faculty of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori-ku, Yokohama 226-8501, Japan.
出版信息
Acta Crystallogr D Biol Crystallogr. 1999 Apr;55(Pt 4):873-6. doi: 10.1107/s0907444998014048.
The DNA dodecamer of (CGCGmo6AATCCGCG) containing 2'-deoxy-N6-methoxyadenosine has been crystallized for X-ray analysis in order to investigate the effects of the modified adenosine on base pairing. It has been found that the crystal changes from one form to another during data collection in a manner similar to a phase transition. The two crystal structures show that this phenomenon, ascribed to differences in humidity, is correlated with a change in the contact angle between the two duplexes.
含有2'-脱氧-N6-甲氧基腺苷的（CGCGmo6AATCCGCG）DNA十二聚体已结晶用于X射线分析，以研究修饰后的腺苷对碱基配对的影响。研究发现，在数据收集过程中，晶体以类似于相变的方式从一种形式转变为另一种形式。两种晶体结构表明，这种归因于湿度差异的现象与两个双链体之间接触角的变化相关。
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