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[乳腺钼靶筛查不能降低乳腺癌死亡率]

[Mammographic screening does not reduce breast cancer mortality].

作者信息

Sjönell G, Ståhle L

机构信息

Kvartersakuten Matteus, Stockholm.

出版信息

Lakartidningen. 1999 Feb 24;96(8):904-5, 908-13.

Abstract

The outcome of a Swedish mammographic screening programme has been studied by analysis of official health statistics for 1987-96. The study series comprised 605,260 women (70 per cent of those aged 50-69 years at inclusion in the mammography programme), representing 4,908,176 woman-years, 1,932,353 mammographies, and 6,713 deaths due to breast cancer. The observed number of deaths was 55 (0.8%) less than would have been expected had the screening not been performed (ns), whereas findings in the Two County Council study suggest that the reduction in mortality should have been 28 per cent (n = 739) for the group and period studied. Thus, the cost of saving a single life was estimated to have been SEK 18-25 million (approximately GBP 1.3(1.8 m. USD 2.36(3.17 m).

摘要

通过分析1987 - 1996年的官方健康统计数据,对瑞典乳房X光筛查项目的结果进行了研究。该研究系列包括605,260名女性(占乳房X光检查项目纳入的50 - 69岁女性的70%),代表4,908,176人年、1,932,353次乳房X光检查以及6,713例因乳腺癌死亡病例。观察到的死亡人数比未进行筛查时预期的死亡人数少55人(0.8%)(无统计学意义),而两县议会研究的结果表明,对于所研究的群体和时期,死亡率应降低28%(n = 739)。因此,估计挽救一条生命的成本为1800万至2500万瑞典克朗(约合130万英镑(180万美元)、236万英镑(317万美元))。

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