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二氧化碳激光内镜下后份部分脊髓横断术治疗双侧声带麻痹

CO2 laser endoscopic posterior partial transverse cordotomy for bilateral paralysis of the vocal fold.

作者信息

Laccourreye O, Paz Escovar M I, Gerhardt J, Hans S, Biacabe B, Brasnu D

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Laënnec Hospital, University Paris V, France.

出版信息

Laryngoscope. 1999 Mar;109(3):415-8. doi: 10.1097/00005537-199903000-00014.

Abstract

OBJECTIVE/HYPOTHESIS: A clinical evaluation of CO2 laser endoscopic posterior partial transverse cordotomy (EPPTC) in patients with severely compromised airway due to bilateral paralysis of the vocal fold.

STUDY DESIGN

An inception cohort of 25 patients over a 10-year period.

METHODS

The CO2 laser EPPTC was unilateral in 15 patients and bilateral in 10. Variables were tested for potential statistical relation to successful rehabilitation of the airway.

RESULTS

The use of the CO2 laser never resulted in adverse side effects. Complications were not encountered. A one-step, successful restoration of the airway was achieved in 68% (17/25) of patients. In univariate analysis, the CO2 laser EPPTC was statistically more likely to be successful if bilateral EPPTC was performed (P = .018). None of the following variables--age, sex, cause of bilateral paralysis, prior treatment, laser parameters, and duration of postoperative antibiotherapy and oral steroids--was statistically related to a successful restoration of the airway. Revision CO2 laser EPPTC, performed in six patients, resulted in an overall 92% (23/25) rate for a successful restoration of the airway. The overall tracheotomy rate was 8% (2/25).

CONCLUSION

The authors' data confirm the safety, ease of performance, and efficiency of the CO2 laser EPPTC in patients with bilateral vocal fold paralysis. This report also suggests that the completion of bilateral CO2 laser EPPTC statistically increases the likelihood of restoring the airway in a one-step surgical procedure.

摘要

目的/假设:对因双侧声带麻痹导致气道严重受损的患者进行二氧化碳激光内镜下后部分横断脊髓切开术(EPPTC)的临床评估。

研究设计

10年间纳入25例患者的起始队列研究。

方法

15例患者行单侧二氧化碳激光EPPTC,10例患者行双侧手术。对各项变量进行测试,以确定其与气道成功恢复之间的潜在统计学关系。

结果

使用二氧化碳激光从未导致不良副作用,未出现并发症。68%(17/25)的患者实现了气道的一步成功恢复。在单因素分析中,如果进行双侧EPPTC,二氧化碳激光EPPTC在统计学上更有可能成功(P = 0.018)。以下变量——年龄、性别、双侧麻痹的原因、先前治疗、激光参数、术后抗生素治疗和口服类固醇的持续时间——均与气道的成功恢复无统计学关联。6例患者接受了二氧化碳激光EPPTC翻修手术,气道成功恢复的总体比例为92%(23/25)。总体气管切开率为8%(2/25)。

结论

作者的数据证实了二氧化碳激光EPPTC在双侧声带麻痹患者中的安全性、操作简便性和有效性。本报告还表明,在一步手术中完成双侧二氧化碳激光EPPTC在统计学上增加了恢复气道的可能性。

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