Boci R, Fall M, Waldén M, Knutson T, Dahlstrand C
Department of Urology, Sahlgrenska University Hospital, Göteborg, Sweden.
Neurourol Urodyn. 1999;18(1):25-32. doi: 10.1002/(sici)1520-6777(1999)18:1<25::aid-nau5>3.0.co;2-o.
To study home uroflowmetry and to compare this method to free or "traditional" uroflowmetry in the evaluation of the patient with symptomatic benign prostatic hyperplasia (BPH), and the relationship between the values of home uroflowmetry parameters and bladder outlet obstruction (BOO). Twenty-five patients (mean age, 67 years) with symptomatic BPH were examined with home uroflowmetry, free uroflowmetry, and pressure-flow measurement. The patients were assessed using the International Prostate Symptom score; digital rectal examination; routine blood chemistry, including serum prostate-specific antigen level; urinanalysis; transrectal ultrasonography; and post-void residual urine. The 24 hr were divided into "active time" (AT) and "sleep time" (ST). AT home uroflowmetry parameters were compared to ST ones. The home uroflowmetry parameters were compared to respective ones of the free uroflowmetry as well and those obtained by pressure-flow measurement. The patients were asked about their opinion of home uroflowmetry. Home uroflowmetry was found to be a simpler and more acceptable method than free uroflowmetry. The mean Qmax of AT was significantly greater than the mean Qmax of ST, but the mean voided volume and mean voiding time of ST were significantly larger than those of AT. There was a close relationship between the mean Qmax at home and the Qmax in hospital, but the voided volume and voiding time measured in hospital were significantly larger than those at home. Home uroflowmetry provided an estimation of BOO for 46% of the patients as low if the home mean Qmax was >14 ml/sec, and as high if the home mean Qmax was <10 ml/sec. Home uroflowmetry was well accepted by the patients and gave more information than free uroflowmetry. In 46% of the cases, an estimation of BOO was obtained with home uroflowmetry.
研究家庭尿流率测定,并将该方法与自由尿流率测定(或“传统”尿流率测定)在有症状的良性前列腺增生(BPH)患者评估中的应用进行比较,以及探讨家庭尿流率测定参数值与膀胱出口梗阻(BOO)之间的关系。对25例有症状的BPH患者(平均年龄67岁)进行了家庭尿流率测定、自由尿流率测定和压力 - 流率测定。使用国际前列腺症状评分、直肠指检、常规血液生化检查(包括血清前列腺特异性抗原水平)、尿液分析、经直肠超声检查以及排尿后残余尿量对患者进行评估。将24小时分为“活动时间”(AT)和“睡眠时间”(ST)。比较AT时段的家庭尿流率测定参数与ST时段的参数。还将家庭尿流率测定参数与自由尿流率测定的相应参数以及压力 - 流率测定获得的参数进行比较。询问患者对家庭尿流率测定的看法。发现家庭尿流率测定是一种比自由尿流率测定更简单且更易接受的方法。AT时段的平均最大尿流率(Qmax)显著高于ST时段的平均Qmax,但ST时段的平均排尿量和平均排尿时间显著大于AT时段。家庭Qmax均值与医院Qmax之间存在密切关系,但医院测量的排尿量和排尿时间显著大于家庭测量值。如果家庭平均Qmax>14 ml/秒,家庭尿流率测定可为46%的患者提供低BOO估计;如果家庭平均Qmax<10 ml/秒,则为高BOO估计。家庭尿流率测定受到患者的良好接受,并且比自由尿流率测定提供了更多信息。在46%的病例中,通过家庭尿流率测定获得了BOO估计。