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Home Urodynamic Pressures and Volume Measurement for the Neurogenic Bladder: Initial Validation Study.家庭尿动力学压力和容积测量用于神经原性膀胱:初步验证研究。
J Urol. 2017 Dec;198(6):1424-1429. doi: 10.1016/j.juro.2017.05.081. Epub 2017 Jun 3.
2
Projecting the Urology Workforce Over the Next 20 Years.预测未来20年的泌尿外科劳动力情况。
Urology. 2016 Dec;98:21-26. doi: 10.1016/j.urology.2016.07.028. Epub 2016 Aug 1.
3
Improving qPCR telomere length assays: Controlling for well position effects increases statistical power.改进定量聚合酶链反应端粒长度测定法:控制孔位置效应可提高统计效力。
Am J Hum Biol. 2015 Jul-Aug;27(4):570-5. doi: 10.1002/ajhb.22690. Epub 2015 Mar 10.
4
Applicability of a disposable home urinary flow measuring device as a diagnostic tool in the management of males with lower urinary tract symptoms.一次性家用尿流测量装置作为诊断工具在男性下尿路症状管理中的适用性。
Urol Int. 2012;89(2):166-72. doi: 10.1159/000338907. Epub 2012 Jul 13.
5
Influences of neuroregulatory factors on the development of lower urinary tract symptoms/benign prostatic hyperplasia and erectile dysfunction in aging men.神经调节因子对老年男性下尿路症状/良性前列腺增生和勃起功能障碍发展的影响。
Urol Clin North Am. 2012 Feb;39(1):77-88. doi: 10.1016/j.ucl.2011.09.005. Epub 2011 Oct 13.
6
Methods and value of home uroflowmetry in the assessment of men with lower urinary tract symptoms: a literature review.方法和价值的家庭尿流率在评估男性下尿路症状:文献复习。
Neurourol Urodyn. 2012 Jan;31(1):7-12. doi: 10.1002/nau.21197. Epub 2011 Oct 28.
7
Age-stratified normal values for prostate volume, PSA, maximum urinary flow rate, IPSS, and other LUTS/BPH indicators in the German male community-dwelling population aged 50 years or older.50 岁及以上德国男性社区居民前列腺体积、PSA、最大尿流率、IPSS 及其他下尿路症状/良性前列腺增生症指标的年龄分层正常值。
World J Urol. 2011 Apr;29(2):171-8. doi: 10.1007/s00345-010-0638-z. Epub 2011 Jan 8.
8
Home and office uroflowmetry for evaluation of LUTS from benign prostatic enlargement.用于评估良性前列腺增生所致下尿路症状的家庭及办公室尿流率测定
Prostate Cancer Prostatic Dis. 2005;8(1):45-9. doi: 10.1038/sj.pcan.4500763.
9
Comparison of tamsulosin efficacy in subgroups of patients with lower urinary tract symptoms.坦索罗辛在伴有下尿路症状的患者亚组中的疗效比较。
Prostate Cancer Prostatic Dis. 1998 Dec;1(6):332-335. doi: 10.1038/sj.pcan.4500267.
10
The importance of the normality assumption in large public health data sets.正态性假设在大型公共卫生数据集中的重要性。
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男性排尿行为:19824 份家庭尿流率图的见解。

Male Voiding Behavior: Insight from 19,824 At-Home Uroflow Profiles.

机构信息

Department of Urology, University of Utah Health Sciences, University of Utah, Salt Lake City, Utah.

Department of Urology, Icahn School of Medicine, Mount Sinai Health System, New York, New York.

出版信息

J Urol. 2021 Apr;205(4):1126-1132. doi: 10.1097/JU.0000000000001504. Epub 2020 Dec 1.

DOI:10.1097/JU.0000000000001504
PMID:33259269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8411883/
Abstract

PURPOSE

Benign prostatic hyperplasia is one of the most common conditions seen by a general urologist. Validated questionnaires provide insight into patient symptoms, however office based uroflow devices are limited by the variability of voiding behavior. Using a home uroflow device, we assessed individual voiding variability, temporal distribution of voiding parameters and the impact of age on voiding.

MATERIALS AND METHODS

Between April 2019 and June 2020, 19,824 unique voiding profiles were captured using the Stream Dx Uroflowmeter and retrospectively analyzed. Age and number of voids were summarized by mean±standard deviation. We used mixed effects models to compare average values and intrapatient variability of voiding parameters to time of day and age. The coefficient of variation was used to assess intrapatient variability.

RESULTS

A total of 637 patients were identified with 625 meeting inclusion criteria, producing 19,824 voids. Mean age was 67 (±10.2) years old, and each patient provided on average 5 (±3.3) voids a day through 7 days. Average intrapatient voiding parameters showed notable variability, where the coefficient of variation for maximum flow was 27.6% (95% CI 26.6-28.6). Early morning voids were associated with higher volume and lower number of voids. As age progressed, voiding profiles worsened in a linear fashion. Afternoon and evening voids were associated with reduced intrapatient variability relative to early morning voids.

CONCLUSIONS

Assessment of 19,824 uroflows using an accurate and precise home uroflow device demonstrates that an individual's voiding parameters vary greatly from day to day, throughout the day, and worsen with age. Multiple measurements performed at home provides a more realistic assessment of true voiding behavior by capturing individual voiding variability and can help urologists make better decisions in patient care.

摘要

目的

良性前列腺增生是普通泌尿科医生最常见的病症之一。经过验证的问卷可深入了解患者的症状,但基于诊室的尿流率设备会受到排尿行为变化的限制。通过使用家用尿流率仪,我们评估了个体的排尿变异性、排尿参数的时间分布以及年龄对排尿的影响。

材料与方法

在 2019 年 4 月至 2020 年 6 月期间,使用 Stream Dx 尿流率仪共采集了 19824 个独特的排尿记录,并对其进行了回顾性分析。用平均值±标准差总结年龄和排尿次数。我们使用混合效应模型比较了一天中不同时间和年龄对平均尿流率参数和个体内变异性的影响。变异系数用于评估个体内变异性。

结果

共确定了 637 名患者,其中 625 名符合纳入标准,共产生 19824 次排尿。平均年龄为 67(±10.2)岁,每位患者每天平均排尿 5(±3.3)次,持续 7 天。平均个体内排尿参数显示出明显的变异性,最大流率的变异系数为 27.6%(95%CI 26.6-28.6)。清晨的排尿量较大,排尿次数较少。随着年龄的增长,排尿模式呈线性恶化。下午和晚上的排尿与清晨相比,个体内变异性降低。

结论

使用精确的家用尿流率仪评估 19824 次尿流,表明个体的排尿参数每天、全天都有很大差异,且随年龄增长而恶化。在家中进行多次测量可以通过捕捉个体的排尿变异性更真实地评估真实的排尿行为,帮助泌尿科医生在患者护理方面做出更好的决策。