Frisch B, Lewis S M, Swan M
Br J Haematol. 1976 Aug;33(4):469-75. doi: 10.1111/j.1365-2141.1976.tb03565.x.
The ultrastructure of the cellular interfaces between erythroid precursors has been studied in both congenital and acquired dyserythropoiesis. The types of cell-to-cell contacts found included highly convoluated interdigitating septate-like junctions as well as apparent confluence of the cellular membranes of adjacent erythroid cells. Such findings are not characteristic of the intercellular relationships found in the normal erythroblastic islands. The erythroid plasma membrane modifications are possibly related to the changes in the plasma membranes of erythroid cells known to occur in dyserythropoiesis and their presence may well contribute to the ineffective erythropoiesis with intramedullary cell destruction which characterizes many dyserythropoietic states.
在先天性和后天性红细胞生成异常中，均对红系前体细胞之间的细胞界面超微结构进行了研究。发现的细胞间接触类型包括高度卷曲的指状分隔样连接，以及相邻红系细胞细胞膜的明显融合。这些发现并非正常红细胞造血岛中细胞间关系的特征。红系细胞膜的改变可能与已知在红细胞生成异常中发生的红系细胞质膜变化有关，其存在很可能导致以骨髓内细胞破坏为特征的无效红细胞生成，这是许多红细胞生成异常状态的特点。
